ackbar03

of course, hindsight is 20/20, but... Why did they accept the deal with the investors?? That seems like a horrible deal? Google search shows they only raised $416mio total, roughly speaking anything above that and below $559mio the investors could have accepted, pocketed a quick and tidy profit, screw everyone else, and nobody can do anything about it. Or is that too naive of me?

You think generative ai/deep learning tools could help with this?

Cultural norms? Nobody really reads zines anymore. I'm not part of that age either but smashing the stack is really a piece of internet history.

I think this was where most people learnt about buffer overflow attacks and return pointer control. I didn't realize they were still publishing. With multi-year intervals lol

Wait, they're mounting starlink on drones? Is that actually a thing?

You heard the man. We're trying to convince people we've faked another landing by landing on the moon

Why doesn't the company pursue it for other purposes? Sounds extremely narrow, as per the comment above. There may be related stuff where it works as a treatment depending on the endpoint?

That's the space Power Rangers

Archive doesn't seem to work for me for bloomberg articles anymore, I dunno why. I can only access ones archived by others

> you need to add in the flower gradually, sifting it through a sieve

This sounds like equal wealth distribution by the state. John would not approve

My understanding is, ideally your clinical trial manages to capture or balance out the different potential factors in genetic variation.

An example of this is when they tested the covid vaccine, they wanted to make sure they had enough participation from African American and other ethnicities since these were usually under represented in clinical trials relative to the population, and there are sometimes subtle variations in the way peoples body respond to drugs depending on their race.

Someone should do a genome manager startup

I would say target discovery is definitely no less important than drug discovery though. Biology is so complex, for a lot of diseases we aren't even sure the targets and pathways are valid. But then again, as per another commenter, I guess it's much harder than it seems, and probably not as easy to monetize as a drug

I would have thought they were pretty well positioned to find new targets for currently untreatable diseases. But maybe they don't quite have the capacity needed to target specific diseases and/or data not granular and clean enough, or not enough capital/runway suitable for that kind of stuff. If they had the sequences for people with diseases such as alzeimers/Parkinson, they could just look for common mutations and see what specifically it affects

I seemed to have recalled there was a bit more than just a mention, but I might have confused it with some other stuff I read. A lot of well known figures seemed to have crossed paths during the early days of the internet which I found pretty fascinating

So is this good or not good research? Can you make up your mind?

My man you deserve every dollar you make from that trade

There's quite a few interesting cameo's, including Robert Morris (Morris Worm) and Paul Graham himself.

Would also be cool if you have some templates for some typical series of funding rounds all the way to the exit in different industries, which we can just load and see (fantasize about) the possible trajectories.

How bout this guy

https://images.app.goo.gl/aqh2AP5tj7JBkVKZ9

what are you on?

ha! someone actually beat me to this comment

＞probably easier to find your local neoliberal and smell his farts for the same effect.

And you would know this because...?

That's why they only offer 10 million.

If you want, you can offer 100mio, I'll join your competition instead

oh sht, this guy can persuade clients and close deals? Better keep him away from the company!

Jesus, Alexandr's like 26. Can you imagine being at the helm of openai at 26

It will probably ask for opposable thumbs and a machine gun

Ilya's going to have to leave right?

I think I read about these orphanages, which mainly took in children from prostitutes after they got pregnant, in that book "Range: generealists are better" or whatever it was called. I'm not sure if its the same ones mentioned in the book. They trained the orphans in a wide variety of musical instruments to perform for patrons or at events, it was their main source of income for the orphanage, and the orphans were in fact very skilled. A lot of the baroque period musicians wrote music to be performed by them.