arijo

Sorry, but not well thought through complete nonsense is not an acceptable answer.

Watch this https://www.youtube.com/watch?v=sUAbqXcSAzg&t=24s

It's a Oxford’s Keto for ADHD & Depression Randomized Controlled Trial

My personal story is with psychosis which is as severe a mental illness as there can be - and I'm very thankful there are doctors and researchers out there battling all the misinformation about metabolic therapies.

People have different brain structures, but all brains are composed of cells and cells depend on their normal metabolic pathways to do their job.

I actually took dopamine reducing drugs for more than 20 years and I do know from personal experience how these drugs mess up people's lives.

So, yes I'm following a ketogenic therapy to, via metabolic normalization, regulate my dopamine pathways, and after 20+ year of misery I finally feel like I have a brain and a life.

I hope everyone has the chance to benefit from this research as I am benefiting, because I do know how painful it is to be prescribed these drugs for life.

It's all in the book. Read it.

When your insulin levels are deregulated, the receptors in your brain-blood barrier became insulin resistant and despite being drown in a sea of glucose your brain cells cannot access it and let their mitochondria use it to produce energy.

Your brain cells then start malfunctioning and neurotransmitter pathways, like dopamine, serotonin or GABA, get messed up.

This is the link from carbs, to glucose levels, to insulin resistance, to the pathophysiology of neurotransmiter pathways which are the SYMPTOMS, not the CAUSE of mental illness.

Read the book.

Watch videos from metabolicmind.org.

There are a lot of researchers working on metabolic health studies as we speak.

Listen, stop playing with serious mental illness.

I suffer from severe mental illness since I was young - ketogenic therapy is evidence based medicine and has changed my life in a way medication never has.

When you downplay this emerging field of metabolic health you're preventing many people to have access to a treatment that can save their lives.

Please inform yourself better - do not careless spread misinformation that can hurt other people.

Did you read the book?

Provide some quotes that support your absolute certainty that this is a self-help book.

I see you did not read the book - if you go to the notes section you'll find references to all the technical papers that support each chapter of the book.

I suffer from a severe mental illness and following a ketogenic therapy has been life changing for me.

It is giving me hope and I see the mind blowing results every day.

It's not a theory to me.

My approach these days is to follow a meditation mantra:

1. Slow down - the moment I'm aware my mind is no longer quiet and alert because of some trigger (internal or external)

2. Stop suffering - I do a quick body scan for the associated sensations along the body, tell myself this is just a temporary mood change, it will go away the same way it made its way into my body and mind

3. Take a deep breadth - I focus on my breadth for a few seconds and relax

4. Let it go - I know I should not blindly believe any thoughts or feelings that take over my mind and try to get back to a relaxed state of mind

I do this all the time not just during a few minutes of formal pratice. Its so ingrained in my way of being that some people close to me say my personality drastically changed.

But there's still a long way to go.

I think the main issue is the unhealthy up and down insulin spikes caused by modern high carbs diets.

My ability to focus deeper and for a longer period of time increased substantially - I'm afraid my IQ is still the same ;)

Thanks. Is that because one can get the basal rate from each weight plateau and then estimate the calorie deficit required to reach a certain weight target?

I guess the protein and strength training will make sure you keep your muscle mass while you are losing fat - is this correct?

It's interesting how mind wandering can be analysed from different perspectives:

1. In meditation the main goal is precisely to free ourselves from the monkey mind that seems to be the cause of all suffering

2. In neuroscience mind wandering is seen as the brain default mode unless we are operating within a goal driven mindset

3. This can also be seen as a kind of reinforcement learning: we train ourselves to notice when we are mind wandering - this process in itself, after some time, conditions the mind to focus on the present moment

4. From a metabolic perspective (e.g. ketogenic therapy), mind wandering can be seen as the result of blood glucose fluctuations that cause mental fogginess and impair focus

In my own experience as a long time meditation practitioner, what really made the difference for me was regulating my blood glucose levels by following a ketogenic diet. The change in clarity of mind and focus were life changing to me.

I write a bit on my experience in my blog:

https://www.feelingbuggy.com/p/how-the-ketogenic-diet-helped...

Just my 2 cents on a fascinating subject!

Spoken too early - I’ve skimmed the blog and it looked like a pretty thorough and likely more relevant analysis than this post.

Some ketogenic therapy experts theorize that a possible cause for those plateaus is due to the body reducing its metabolism due to what it thinks is an abnormal calorie deficit, entering survival mode - then after a period of adaptation it returns its metabolism to normal and the weight loss process continues.

I didn’t happen to find a plateau yet but surely will share the data if that happens.

Thanks for the insight - I’ll do some research on that.

I don't intend to use the model to predict more than a couple of weeks - the fact that it has no data to predict more than that is not that a big deal for this use case.

Not very important, but the weight loss curve usually decelerates with time and this pattern is not captured by a straight line either - as i say not a big deal, it just happens that by using a simple DNN model for a simple curve I don't have to spend time choosing the type of function I want the data to fit.

Also the model will improve as the number of measurements that are available increases.

Your comment does make sense, I just think for this use case and short term prediction it's not a major problem.

I'd be happy to learn how you'd apply some renormalization techniques to reduce the number of parameters and prevent the overfitting - I'm just a noob very curious to learn as most as I can about practical deep learning techniques.

I actually do that frequently to comply with my ketogenic diet - take a photo of the macro nutrients quantities, calories from the nutrition facts table on the food package and use ChatGPT or some other LLM to calculate the estimated calories per portion.

You can then validate the data by tracking your lost calories (calculable from your lost weight - I do it each week) and compare with the predicted weight lost calculated from the vendor 's nutrition facts table.

Ha ha, no worries - I'm eager to learn from you guys as well :)

I think most of the classical statistical methods for curve fitting happen to be some kind of variant of using least squares on a manually chosen parameterizable function - you'll have to chose between a linear, polynomial, exponential or some other moire complex forms.

The nice things of using a simple feedforward DNN is that it will automatically infer both the nonlinear function structure and parameters and for simple basic use cases like this that don't require a lot of training it works well and you can even validate the fit visually by looking at the graph output.

I wold love to join - I sarted reading the book a while ago but never finsihed. Liked a lot what I have read so far though. Sent you an email.

Being genuinely interested in others seems like a life lesson many of us should internalize from an early age. Thanks for this deep insight :)

Thanks for having taken the time to provide these suggestions. To be honest I must say that I have all of those books on my personal library though I appreciate you having shared your personal reading experience, one always gains a deeper insight from another person’s perspective and insights from reading the same books :)

You're welcome :)

haha thanks for the correction - I was under the Turtles All the Way Down mindset :)

Makes intuitive sense, thanks for the insight.

A second layer blockage for the secondary particles wouldn't have to be as dense or am I missing important physics?

(I guess a lot of gamma radiation would still reach this second layer so please ignore my question :)

You don't need to block gamma radiation completely to increase the electronics reliability :)

Maybe you could improve the system availability considerably by a bit of gamma radiation protection combined with some more parallelism of the components ..

Actually this is a good question - there's a lot of control engineering research on Data-Driven Control Systems.

Check Steve Brunton youtube channel, he is one of the leaders in this area: https://youtu.be/gb_C9LcjDSI?si=xUjqUZ9-0MIFohX6

> Another interesting thing SpaceX is doing is to use consumer-grade chips in triple redundancy configurations instead of using $100,000+ radiation-hardened aerospace/defense grade chips.

This has been known in the high availability and safety systems industry for a while and a good book to learn these reliability engineering techniques is "Reliability Evaluation of Engineering Systems".

The book is available on amazon: https://a.co/d/1nH824K

I never thought of using fluid dynamics in the rocket stabilization algorithm—maybe it's something that could be useful to prevent many of the accidents involving liquid-transport trucks

Not only have I done my research

Youtube Videos

https://youtu.be/PeqQd4_xveI?t=43

https://youtu.be/G0lTyhvOeJs?t=421

https://www.youtube.com/@metabolicmind

Books

https://a.co/d/cUAgokV

https://a.co/d/32zSKzo

https://a.co/d/acVla0y

As I have been following the ketogenic diet and wrote about it

https://www.feelingbuggy.com/p/finding-hope-after-decades-of...

https://www.feelingbuggy.com/p/my-journey-from-mental-health...

https://www.feelingbuggy.com/p/how-the-ketogenic-diet-helped...