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> Third, caching without taking the context into account will probably lead to data corruption one way or another.

One can only hope it's data corruption and not a sensitive data leak.

What solutions are 100% accurate?

> How does any Wordpress developer know they are not going to be next? Or all of the third party plugin providers? Or theme makers? All of them heavily use Wordpress branding in their services, few contribute to the open source.

Easy, just don't be too successful.

So why should someone use WordPress, knowing one person with enormous conflicts of interest determines which companies are allowed to host it?

WordPress has always had a phenomenal admin editing experience relative to what else existed. That on top of a dogmatic adherence to backwards compatibility made the free (and paid) theme/plugin ecosystem thrive.

Does anyone know why WP engine doesn't actually support multiple post revisions by default? I worked with WordPress significantly quite a while ago and found it to be an absolute dumpster fire of a codebase. It wouldn't surprise me in the slightest if running a scalable WP host required tamping down on some things.

Not OP, but it's certainly not by leaving drugs unapproved in the US that have been in wide use in Canada, England, Japan, etc for years (and in some cases decades). The incentives are so misaligned for the FDA that the bias for inaction is enormous.

I also find it a bit patronizing that a federal agency determines whether or not a drug they've deemed safe has enough upside potential for me. That's a value judgement I'd like to make for myself.

Sorry if this sounds harsh, but the FDA's inability to approve drugs inside of a decade has personally impacted me quite a bit.

I'd never heard this before, but it's really interesting. This reminds me a lot of when Hollywood tried (successfully?) to bully Netflix out of adding a playback speed button. I'm not sure to what extent creators should be allowed to control how people consume their media.

> Now, that said... is $42,000/yr a reasonable price? Fuck no. On a purely humanitarian level, it's unacceptable, and if we're just looking at Gilead's bottom line, I'm sure they could price this drug for a whole lot less and still recoup the cost of clinical trials (and then some).

Is it unacceptable if the company decides not to make the drug in the first place? The default alternative isn't that we have the drug for less, it's not having it at all.

Faceting over even small result sets and producing the relevant counts is really hard for postgres, and caching tends to be impossible due to the combinatorics of the problem. There's some discussion around supporting better indexing options here that is relevant: https://www.postgresql.org/message-id/CAJqPDh9o%3DoxRP%3DxZh.... Practically, https://github.com/cybertec-postgresql/pgfaceting is the best bet for people who must use postgres even though it still uses a manual maintenance step.

Pay for the sync feature, it works seamlessly.

Reading this thread it's impressive how little people know about competitive gaming while simultaneously knowing how to fix the cheating issues.

Most decisions are mixed or more one sided than following the standard "political lines", but those cases never get spoken about.

> governments signing contracts that guarantee they'll pay $X hundred million for a solution BEFORE the research has been done

Did you say "hundred million" intentionally? Because the average cost of a drug has been estimated in the billions for over a decade now. [1] I'll take a listen to the podcast, I'm generally skeptical of the government deciding funding levels since they're likely to be worse at assessing demand than consumers.

[1] https://www.appliedclinicaltrialsonline.com/view/tufts-cente...

They expire after 20 years IIRC. There is some shenanigans that go on with "evergreening" where they try to expand it out for longer, but it's generally an effective system.

The ars article says 10 billion to make.

Is this the cost for the "pill" after research is done? The first pill is the one that costs billions after all.

Not a lot. https://www.science.org/content/blog-post/rep-ocasio-cortez-...

One thing I'm curious about is the DOJ took specific aim at Apple Pay and how Apple was creating a monopoly by limiting third party apps from making payments. I'm personally a bit torn, because it seems like the preventing third party apps from accessing the secure enclave is a security feature.

> People can get so irrational when it comes to the cost of software. The same person who'd pay hundreds of dollars for a cleaner, or a gym membership, will swear up and down that 70 bucks a year for an online bodyguard is highway robbery.

Often while refusing to work for less than six figures as a SWE, hating on companies for seeking VC funding, dismissing non open-source approaches, and then complaining why there aren't more alternatives :)

> Another weird/fascinating factor for me at least is that less convenient access to a toilet seems to correlate with less symptoms. When I'm hiking in the mountains I never seem to have a high frequency of needing to take a dump.

Not Chron's but a related disease. For me the symptoms are strongly correlated with how embarrassing it would be if I had to go. So hiking in the mountains is pretty relaxed (unless it's a date or something), just find a spot off trail. In the chair at the dentist with instruments in your mouth and a bib on? All of a sudden I've gotta go.

> Blocking pharma ads would help a lot as well.

I don't really see how blocking ads for things help, I also think they serve a really valuable purpose. IME Doctors are so stuck in their first decade of work (CE programs are mostly a joke) that there actually needs to be a forcing function to get them to learn about new drugs. If they start irresponsibly prescribing drugs then that's not the fault of a company advertising drugs that have gone through the most rigorous approval process that exists in the world.

I feel like it also helps them get an edge in the healthcare sector, which has buckets of money in the mix.

Remember when Firefox was the new hotness because it blocked ads?

Sure, though I can't cite the source off hand, I remember the statistic being something like a bachelor's degree of any kind increases earnings by roughly 17k. It's very hard to consider this anything other than a bargain for the average bachelor's student, interest included. AFAIR the stats show that the people who are truly destroyed are the ones who get loans but don't get the piece of paper.

Reminder that the average student loan debt is somewhere in the ballpark of $40k with the median being a little lower. I've found that most of the coverage on student loans misleadingly focuses on outliers.

Edit: downvoted for factual information :-/.

The justice system is filled with all sorts of this stuff, sadly. Claiming they can match a shell to the gun it came out of, blood spatter, etc. My favorite example of this existing at a micro scale is when a professor claimed she could determine age, sex, and race from the footprint of a suspect.

[1] https://greensboro.com/anthropologist-testified-nationwide-g...

I used Kagi to summarize the transcript:

- A serious SSH backdoor was discovered in the xz Linux compression library, allowing attackers to compromise SSH servers.

- The backdoor was discovered by Andres Freund, a Postgres developer, who noticed suspicious CPU usage and login attempts on his systems.

- The xz backdoor allowed attackers to bypass authentication and gain root access on compromised systems.

- Microsoft faced significant criticism from the CSRB (Cybersecurity Review Board) for a cascade of errors related to a China-based hack.

- Ukraine was able to leverage an old WinRAR vulnerability to hack into Russian systems as part of the ongoing conflict.

- There have been recent "MFA bombing" attacks targeting Apple users, combining push notifications and social engineering.

- A ransomware gang leaked stolen Scottish healthcare patient data as part of an extortion attempt.

- Renowned security expert and author Ross Anderson passed away.

- The episode features a discussion with Andres Freund about his discovery of the xz backdoor.

- The podcast sponsor, Island, discusses how enterprises are moving away from VDI (Virtual Desktop Infrastructure) towards security-focused enterprise browsers.

> The irony of it all is that MongoDB actually matured and you do not have to jump through hoops to have, say, transactions.

Are transactions still limited to a single document in Mongo?

Go forth and prosper https://www.emacswiki.org/emacs/GlassesMode.