burpsnard

It's been done : http://www.artmarcovici.com/qentis

Presumably at least some of the seed funding for these research facilities is from the majors, who likely in turn lease research capacity to them. Interesting model

Part of the controversy is around what constitutes a demonstration of safety.

One is "i fed it 50 rabbits and they were all fine the next morning";

another is "LD50 (50% died) within 24hrs of consuming X milligrams per kg of rabbit weight, which well above expected levels present in food";

Another is "more tumours in these 500 rats who were fed glyphosphate - exposed crops, than in these other 500 genetically identical rats fed the same but organic version, after 9 months"

One i saw, was a banking backend; stored blobs retrieved by accountnumber from the mainframe were passed to mid-tier servers that mounted the blobs as r/w db instances.

Sort of like piles of sqlite db's on S3

IMSI, IMEI, MSISDN, etc.

Systems to associate 'burner' phones to individuals, with patterns of metadata, have been commonplace for decades

https://github.com/kimgr/asn1ate/blob/master/testdata/public...

I once took a call in our office, looking for a "mrs x y". I said sorry noone of that name here. The others come back from lunch, turns out "x y" is a legal alias of colleague "v w", and it was the bank calling.

An unexpected gift

We've been hearing for years about accelerated drug candidate discovery through better tech and automation, and anecdotally a boom in clinical trials informatics etc, so not surprising

Yes.. fda approves combination pills seperate to each drug on it's own. While i'm not a pharmacologist, it dies seem odd

Their method would miss the likes of Blake, Van Gogh, Galileo, ...

I'm suddenly reminded of the hours i spent noodling around with sgml.xml entity catalogues (™ © etc)

Freediving

There's arguably a market for commoditised secure messaging/queueing, baked into the standard radio silicon, that's a few steps ahead of sms.. Finance, email, voicemail, etc. P2P.

I had good ux with realvnc, maybe novnc, ..

If you're pulling in things from a dozen or 2 different domains, it gets expensive (In milliseconds) for client dns lookup, tls negotiation, when added all up.

strace -fe file,network

That's a reason to avoid dynalangs. Otoh, java and .net have ears and assemblies

that libc update spawned a wealth of dependency solutions. And 'dll hell' of course

For me, no way.

On balance i feel more enabled than disabled. You can argue my perspective is skewed, and i yours.

I wish there was some way to give aut insight to neurotypicals, other than reading PKD on LSD.

For every 'cure' i hear of, i wonder can it be used to mane an NT autistic ?

Also: i suspect a lot of debilitating brain diseases and injuries get misdiagnosed as 'autism' as the criteria are very blunt.

Well, as the golden leaves fall from trees in autumnal mists, i can tell you about that time Jimmy's dog scooter, fresh from chasing ..

Cough. Yeah it's filler

'beware of the leopard'.

If its mostly on disk, you're paying ms for block io; get more iops.

If the index used are sensitive to low key diversity, fix that, and maybe shard.

You might prefer a vm type with nvme.

If u can divide the data into more small ones, more indexes and cache fits in ram.

Also, cluster data by what works, time, region, userclass, etc.

Only decompress the blobs at point of use.

Design your app to need only small fast data which cant be cached.

Etc

They still see traffic to an IP, and the hostnames in the certs. Also the request/response lengths can reveal what was fetched

It's educational to try.

I had to tunnel dns through openvpn to make dnssec reliable.

On a wifi router, there's loads of leakage; mdns, ntp, things devices do to check for captive portal, weather apps, etc etc.

You can mitm https, but breaks hsts sites, unless you hack your browser

Same as a rest api

Used to do this by replacing slow queries with a dozen joins with stored procedures,insert/update/delete triggers, materialized views.

The mindset was correctness and validity of a detailed and interrelated collection of known facts, at rest on disk.

Merging 2 of these, say when an insurance Corp buys a competitor, took detailed and painstaking effort by people with both the domain and systems knowledge.

It's very different now,with Json doc stores, where in 5 years time noone will know what timezone that happened in, or if this person is that person with different name because of lossy utf8->ASCII .

When-i-were-a-lad, it went SQL -> views -> stored procedures -> ProC

I suspect they are selling to founders who are rich enough that they want to startup mostly for the social interaction

ermogourd kids it's IRC, ferchrissakes. with oh yeah bots and file transfer and groups.

i heard they were throwing money at integrations with everything, had a bumpy ride scaling (mysql master-master ffs) and had vague plans for AI that'd help automate your org, not sure where that went. But the VC wants exponential or bust, so there you go.