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cactusfrog

286 karma · joined March 6, 2022

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cactusfrog··on The Dire Wolf Is Back
We have robust cloning protocols for dogs. For some reason dogs are really amenable to cloning.
cactusfrog··on Databases in 2024: A Year in Review
The joke is that his greed/ unwillingness to squeeze margins has made the entire database company ecosystem possible.
cactusfrog··on Things we learned about LLMs in 2024
Every waste of money is not a Ponzi scheme.
cactusfrog··on Array Languages for Clojurians (2020)
It’s a closed source POS with unpredictable performance. Talk to people who have actually been forced to use it and many have terrible experiences.

https://news.ycombinator.com/item?id=16170955

cactusfrog··on Array Languages for Clojurians (2020)
I’m glad they are wasting Walmart’s time and money.
cactusfrog··on Array Languages for Clojurians (2020)
It isn’t a suitable language for data science and lacks the ecosystem of Python.

For example, people will write Eden files to parse data, which involves creating a really complex DSL for every file for import.

They will try to use Datomic as a database, which requires using datalog and does not scale.

The worst part is the clojure users are convinced it is somehow better, and ignore the business use case.

I feel bad for companies because it clearly isn’t a good fit and those devs will hire all their friends and do nothing for five years.

This happened at an organization doing cancer research, so the selfish cultists ruined a chance at understanding immunotherapy by focusing on writing clojure rather than doing science.

Recursion pharmaceuticals also had this problem, and had to rip out all of the clojure from their system.

cactusfrog··on Advent of Code 2024
Why isn’t the input a csv?
cactusfrog··on Advent of Code 2024
I just did this in a few lines of python with numpy. I don’t understand why the input isn’t a csv.
cactusfrog··on London's 850-year-old food markets to close
This is a gamblers ruin problem action.
cactusfrog··on Scientific Visualization: Python + Matplotlib (2021)
I’m working in biotech. I think creating “curated” materialized views with dbt + datawarehouse or duck db + using webgl with d3 will be best long term solution https://blog.scottlogic.com/2020/05/01/rendering-one-million... .

Matplotlib works well for static plots. Altair and others freeze at around 4000 data points, which is crazy. Streamlit + matplotlib is impossible to maintain but is quick to get up and running.

cactusfrog··on Scientific Visualization: Python + Matplotlib (2021)
Interactivity is not desirable in all situations. For static figures, matplotlib is still king.
cactusfrog··on Show HN: Meet.hn – Meet the Hacker News community in your city
Twitter/X keeps spamming me with NSFW things so I deleted it
cactusfrog··on With 'digital twins,' the doctor will see you now
A significant amount of health issues result from medical noncompliance. A digital twin might be useful for finding ways of manipulating patients into taking care of their health.
cactusfrog··on Julia for Economists (2022)
I think it has correctness issues
cactusfrog··on You got a null result. Will anyone publish it?
Just write a preprint or a blog post
cactusfrog··on Scientists discover a new hormone that can build strong bones in mice
Probably promote cancer cell growth as well
cactusfrog··on Scientists discover a new hormone that can build strong bones in mice
Bone density loss in space is estimated at a loss of 1-2% of total bone density per month of microgravity exposure. The worst cases of terrestrial bone loss are around 5% of total bone mineral density per year.
cactusfrog··on Typst: An easy to learn alternative for LaTex
Yes, this is one of the major problems with this. I don’t like pdfs
cactusfrog··on Immunotherapy Is Changing Cancer Treatment Forever
Biochemical engineering exists as a discipline and focused on “scale up” of production problems like these. Robots are involved, but most of the time the process is modified to a more stable one.
cactusfrog··on Lies, Damn Lies, and Data Science
“There is an immense diversity, but also disparities in skill, expertise, and knowledge among Data Scientists. The difference in skills between a data scientist with - say - a Bachelor in Physics and a data scientist with a PhD in Computer Science is comparable to the difference in competence between a certified nursing assistant and a surgeon”

My experience, is that the longer someone works in academia, the worse of a coder they are. I’d rather have someone with 5 years of industry experience over someone fresh out of a PhD program.

The author has a PhD and is trying to impose the flawed hierarchy of academia onto tech. This push should be resisted.

cactusfrog··on The one-year anniversary of my total glossectomy
The Mayo Clinic sounds like a garbage healthcare provider.
cactusfrog··on Squarespace to Go Private in $6.9B All-Cash Transaction with Permira
You have to pay enough to convince everyone to sell. The trading price is the marginal price of buying one more unit of stock, not a representation of the stock price at which every owner will sell.
cactusfrog··on Whole-body magnetic resonance imaging at 0.05 Tesla
This is not true, but it is a major challenge. See https://www.pathai.com/
cactusfrog··on Georgia Tech, Meta create open dataset to advance solutions for carbon capture
Yeah. One application that I’ve heard is retrofitting indoor animal farms to capture methane and reduce methane emissions.
cactusfrog··on Georgia Tech, Meta create open dataset to advance solutions for carbon capture
Should carbon capture should be worked in secret because mentioning it delivers false hope?
cactusfrog··on Georgia Tech, Meta create open dataset to advance solutions for carbon capture
Gas separation has many applications.

If Google developed an AI model for cancer detection in MRI scans, you wouldn’t claim that “AI is not for what people think it is for” because Google also uses AI models for advertising.

cactusfrog··on Rama is a testament to the power of Clojure
I don’t believe I’m exaggerating. You can replace “Clojure” with “Jesus” in the linked article and it still makes sense.
cactusfrog··on Rama is a testament to the power of Clojure
The Clojure community is extremely cult like. I worked with a dev who tried to push Datomic, and despite the huge flaws with his system, and the fact that it was closed source, he would continuously tout how much better it was than a relational database. I don’t believe the hype.
cactusfrog··on Cost of developing new drugs may be lower than industry claims: trial
People seeking to maximize profit are not in favor of expensive clinical trials and are not lying about how expensive they are.
cactusfrog··on The Vision Pro is a flop
Apple started out as a personal computer company—which was a radical concept because there was no good answer to “What are regular people going to do with one”. Mainframes and terminals were useful, but personal computers only had minor applications.

The Vision Pro product is inline with this philosophy of building a good product with no clear purpose and letting users figure it out. It is going to take years for someone to come up with a good use. Think about how long it took AirPods and Apple play to catch on.

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