code51

You see I'm also a human being such as you who values life and people. It's a bit harsh to comment about my world view sarcastically like that.

I was just voicing something about the process: biology is a complex thing and longevity is not attacking things from a metabolic, complex-system viewpoint. As we see here, we are after single pills or single gene activations to carry us to a healthy state. I doubt infinite health unlocks in such form.

Another point is, if you transform yourself to this new state that's immortal but lose most of the biology that makes your body human, what does it mean? (reference to Leto Atreides II here maybe)

Why do people suddenly make it unethical to view death as most-probably-inevitable for human beings?

I don't quite understand the premise of longevity research.

Isn't there a concept similar to "no free lunch" in biology? Infinite, cancer-free lives sounds just too good to be true. Something sounds off about that.

Am I right in understanding that all these companies are actually making deals for on-demand use in the future?

Which use cases cannot do without Snowflake or Databricks?

What are the next best materials to test according to br-bcs theory?

We thought Oppenheimer was the way to instill a love of physics to young people but turns out LK-99 was the way to winning people's hearts and minds to delve more into physics.

Damn, why is nobody talking more about the theory of it?

What I see to ponder:

- (1970, brinkman, rice) "application of gutzwiller's variational method to the metal-insulator transition"

- (2001, hyun-tak kim) "extension of the brinkman-rice picture and the mott transition"

- (2002, hyun-tak kim) "extended brinkman-rice picture and its application to high-Tc superconductors"

- (2021, hyun-tak kim) "Room-temperature-superconducting Tc driven by electron correlation"

even briefly reading relevant research (other than these papers) says even if a group could not replicate lk99 at first try, there's more to it. cooking the right way should be insanely difficult because this is a probabilistic event after all. should not be happening homogenously and should not be happening in a wide-band of parameters. I think the groups will eventually reach a narrow range of parameters to replicate but will take a lot of effort.

I slowly started to think Apple knows there will be a golden hour to jump on a mature, economic LLM. Until then, they are probably watching without a massive investment into LLMs if it's not drastically changing their products.

Retry. It'll work. (Brave tested)

I would still be able to use 2013 Macbook Pro if I could have someone around who understand that GPU related issue would be solved by "holding u8900 chip down with rubber material"

https://www.youtube.com/watch?v=lumJ0cN5oyY

https://www.reddit.com/r/macbookpro/comments/ek0pmi/comment/...

However, Apple declares your device "vintage" and repair shops avoid it like the plague. Because they only know who to replace the entire board. That's when you device to buy another laptop.

This "GPT4 evaluating LLMs" problem is not limited to this case. I don't know why exactly but everyone seems to have accepted the evaluation of other LLM outputs using GPT4. GPT-4 at this point is being regarded as "ground-truth" with each passing day.

Couple this with the reliance on crowd-sourcing to create evaluation datasets and heavy use of GPT3.5 and GPT4 by MTurk workers, you have a big fat feed-forward process benefiting only one party: OpenAI.

The Internet we know is dead - this is a fact. I think OpenAI exactly knew how this would play out. Reddit, Twitter and the like are awakening just now - to find that they're basically powerless against this wave of distorted future standards.

When sufficiently proven to pass every existing test on Earth, every institution would be so reliant on producing work with GPT that we won't have a "%100 handmade exam" anymore. No problem will be left for GPT to be tackled with.

Where would they advertise their Discord servers though? You still need to use the Reddit platform to carry over large user bases - which means at one point mods should briefly end blackout. But how to coordinate that without giving in?

Could this potentially help schizophrenia, emotional regulation, impulsivity, reward processing, ADHD etc because of an improvement in functional connectivity?

How on earth this tweet is HN-worthy?

Where we're going we don't need acquisitions.

Did you watch Rick Beato's take on AI effect on music? Monetizing music is a totally different thing that requires fan interaction and that takes both time, a live avatar (human or not). I'm thinking when a group comes up with a live avatar that can do concerts for AI songs and interact with fans, then monetization is doomed. Not for now though...

This runs amazingly fast on M1/M2 Macs (MPS device).

This will just come to the point: "8 billion people have a brain and 99% of them use it wrong. a thread"

Living with doubt is not easy on our minds, that's why. Today we know there's a portion of fake content there already but we're not living with the doubt that %100 is fake.

End of the internet as we know it. Everything will be fake. Maybe-human-zones will be created (again... by startups) but nobody will be sure whether there is actually a human on the other end.

Face-to-face experiences and carefully planned group activities will start to earn a "premium" status. People will be divided: the ones who prefer the virtual and the ones who prefer the physical. The ones losing the physical contact in the process will experience more and more mental health problems over the years.

The biggest impact will be on the election process and democracy as we know it.

I wonder whether autogas (LPG) systems are the cleanest alternative as of now. Until recently the main problem with sequential autogas was sudden explosions of cars with faulty units. Did it get safer as well?

Yes, sorry, I didn't frame it well. I meant the possibility of breaking your properly functioning state of consciousness.

I find it so ironic that on one hand, we are placing great value on achieving consciousness with artificial intelligence and yet, we place so little value on our own.

If this "consciousness" thing is so hard to get, then why do we try our best to get rid of it through alcohol, recreational drugs etc ?

You're surely joking when comparing LSD to foods, right?

Please name one single food that can bring down all your psychological defence mechanisms in one go.

> In a perfect world, health experts say they'd like everyone would get the more expensive polio shot which is incapable of mutating into a dangerous, circulating virus.

but then...

> Mass immunization campaigns with the more expensive yet safer injectable vaccine, he says, are nearly impossible in some of these places. There simply isn't the infrastructure or trained medical staff to carry out such campaigns.

So, let's try to understand this: if we throw a boatload of money onto this problem, is it possible to eradicate polio using that decent, more expensive vaccine?

or... do we have a theoretical misunderstanding of viruses?

If I'm not mistaken both IPV and OPV is applied to children in national immunization problems of developed countries. So there must be something still missing in IPV.

Mark Zuckerberg has a historic opportunity to completely reverse public perception in his favor and offer the best bet against OpenAI.

He is in a great position to do this because a paradigm shift happening to search business doesn't have the heavy effect on them that Google is subject to. Yes, content and ad business is also experiencing a paradigm shift but Meta is better positioned to rework their platform and cope with AI-generated content through a driving force (not control but support) over the most popular content generation tool out there - LLaMA and any upcoming variants.

Historic moment and I think Mark deep down wishes all that VR money went to AI instead.

It’s interesting that (clearly visible) text parts that cannot be handled properly by most OCR approaches also get left out by SAM in auto-predictions.

adding another example to reflect the high influence of style and why either contextual awareness or voice-to-voice guidance is essential for these tasks:

Steve Jobs (cloned voice) reading: "Do not go gentle into that good night"

- https://soundcloud.com/kynes-0/steve-jobs-cloned-voice-do-no...

Sounding quite authentic to me. I tried to compare:

Sentence: "Undoubtedly the biggest global event that occurred in 2020 was the COVID-19 pandemic."

- https://soundcloud.com/kynes-0/steve-jobs-cloned-voice-bigge...

Sentence: "we've been working on artificial general intelligence for many years, and we believe that we're on the cusp of a major breakthrough."

- https://soundcloud.com/kynes-0/steve-jobs-cloned-voice-break...

Research about military offspring ratio seems to have focused on various environmental and occupational exposures, including:

- radiation

- boron

- g-forces

- polychlorinated biphenyls (PCBs)

- dioxins

- pesticides

- lead, and other metals.

(1961) Snyder Rg. - The sex ratio of offspring of pilots of high performance military aircraft.

"A statistically significant (.01>p>.001) preponderance of female offspring born when fathers flew fighter-type aircraft prior to conception was found. Of 94 children conceived and born under these conditions 59 were females giving a sex ratio males per 100 females of 59.3 as compared with the expected ratio of 105.37 obtained from registered births in the U.S. total population in 1950. It was also found that when fathers flew multiengined types of aircraft prior to conception they fathered 15 females and 25 males a sex ratio of 166.67. When fathers did not fly at all the results were 35 females and 53 males a sex ratio of 151.42. The sex ratio by parity was closer to expected. Normally the sex ratio shows a continuous drop at each succeeding pregnancy. Here when the fathers flew transport types of aircraft or did not fly at all prior to conception the same drop was apparent. However a significant reversal occurred when fathers flew fighters prior to conception of each child: the ratio successively increased with each succeeding birth."

Terrell et al. (2011) said: Snyder was the only researcher who used detailed military flight logs to calculate the number of flight hours for each pilot, and the only author to focus on flights during the critical window of spermatogenesis.

- (2009) Å. Irgens, L. Irgens. Male proportion in offspring of military air pilots in Norway

"The male proportion was 36.9%, the male proportion in the reference population was 51.4% with a relative risk 0.72 (95% CI 0.57–0.92). "

But there is also research countering this:

- (2019) Kaitlyn Huegel Mayer, Trimble L.B. Spitzer. Offspring gender rates in active duty fighter pilots and flight officers.

reports offspring ratios similar to general population.

Yet, there seems to be an association with more working hours:

- (2009) Rebecca Baczuk, Anthony Biascan, Erik T. Grossgold, Ari Isaacson, J. Spencer. Sex ratio shift in offspring of male fixed-wing naval aviation officers.

"Although the ratio of male offspring from all participants in our study, aircraft groups, and aircraft supergroups was not statistically significantly different from the general population, this study provides statistical support that there is a sex ratio shift among offspring of male aviation officers when they fly more hours during the 11th month before birth. Furthermore, for officers who fl y carrier-based aircraft, that shift is even more dramatic as they approach and exceed 50 hours per month. "

You might think about G-forces but there's also research about submariners:

- (2019) Kathleen E Kramer, S. Raiciulescu, C. Olsen, K. Hickey, M. Ottolini. Altered Sex Ratios in Offspring of U.S. Submariners Urban Legend or Fact - Do Submariners Have More Daughters?

"The submariners surveyed reported greater numbers of daughters than the general population, especially when on sea duty or in regular contact with submarines during shore duty. Further study should be done to confirm results and explore possible etiologies of differences in sex ratio."

We should also note (2011) Terrell states:

"There is some evidence that the endocrine disruptors, dioxin and PCBs, are associated with altered secondary sex ratio. Dioxin exposure is associated with a lower male:female sex ratio in offspring of exposed men, while PCB exposure is associated with a higher male:female sex ratio in offspring of exposed men."