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hazbot

231 karma · joined August 14, 2018

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hazbot··on mRNA Cancer Vaccine Reprograms Immune System to Tackle Glioblastoma in 48 Hours
You could both be right, especially depending on where you live and work.
hazbot··on mRNA Cancer Vaccine Reprograms Immune System to Tackle Glioblastoma in 48 Hours
When I got my AstraZeneca vaccine (in 2021?) I remember it was common knowledge that fatal blood clots were a side effect, and from the evidence at the time I estimated that the chances of it killing me were 1 in 500,000. Have those odds changed with new information?
hazbot··on The darker side of being a doctor (2017)
With doctors you can parallelize treating different patients pretty easily.
hazbot··on "If this one guy got hit by a bus, the software would fall apart."
But it's also the beauty that a few people can create so much value.

And how many of these projects couldn't be picked up and urgently patched if the proverbial bus does come along? Like it wouldn't be pretty, but would it be possible?

hazbot··on I Put 4M Suns in a Black Hole over New York [video]
I think from the outside, it doesn't matter whether the mass is uniformly distributed throughout the volume or concentrated at the centre - you would feel the same force of gravity. (I'd be interested to hear if there is an experiment you could do just measuring gravity to differentiate between the two!)
hazbot··on Is the Sun Conscious? (2021) [pdf]
>>> If we were to somehow come to believe that consciousness is just an illusion--no more than a biochemical phenomenon, and no more special than transistor switching.

I believe this and yet I personally seek to inflict as little horror as possible, and am moderately restrained in the amount of force I believe the state should use.

hazbot··on Math writing is dull when it neglects the human dimension
I don't think the point here is to make a math paper understandable to a lay person, but rather make it interesting and contextualize it for other academics.
hazbot··on I Put 4M Suns in a Black Hole over New York [video]
Mass divided by volume encased by the event horizon?
hazbot··on Weather forecasts have become more accurate
Cool! If you end up wanting to expand beyond just the nearest weather station (forgive me if I've misunderstood your process), you could look into ERA5 - free Numerical Weather Prediction 'reanalysis' of past weather on a regular grid. openmeteo has some open source tools for extracting time series data from it.

But, although you get good spatial coverage, the drawback is 'the map is not the territory' - the model's representarion of reality doesn't perfectly mesh with the weather on the ground.

hazbot··on Weather forecasts have become more accurate
This is probably because of either poor sensor coverage, or a stale (old) forecast. Many weather services do not issue 'nowcasts' that constantly update with the latest weather observations (it's a hard and interesting problem), but rather a single forecast say 4x a day as the latest Numerical Weather Prediction model run comes in.

Fwiw, I agree with your bemusement and scorn - it's not good enough! (I say this as someone who has had roles where I issued these 'always stale' forecasts)

hazbot··on Weather forecasts have become more accurate
Depends, the "optimal" forecast can be very sensitive to the scoring metrics used.

E.g. Darwin in Australia's tropics - persistence forecasting (as you describe above, just predicting the weather the day before) does very well on a metric like 'mean absolute error'. But has no practical skill at forecasting a severe tropical cyclone (aka hurricane/typhoon)! Many are willing to accept some level of false positives and a higher mean absolute error, because the cost of a surprise cyclone is so devestating.

hazbot··on Why Do Universities Ignore Good Ideas? – Mind Matters
But sport is by definition set up so what is measured is the result we care about.

We would perhaps not care so much about the "vicious cycle" if the incentives were aligned with "good" research. If cancer gets cured, at the end of the day I'm not going to lose a lot of sleep over how. But the concern is the incentives are misaligned in favour of exploiting the metrics instead of "good" research.

hazbot··on Why do tree-based models still outperform deep learning on tabular data? (2022)
model.predict() is pretty easy to call, but judging the validity of the model is still hard and very manual. Linear model is less flexible and powerful, but easier to analyse/validate.
hazbot··on Can Marriage Be Saved?
Eventually, those who disagree will die out.

What a conclusion!

hazbot··on Selfish reasons to want more humans
I think they are quite upfront about their values, and I suspect they would quite likely be OK with being labelled human-centric, as would I!
hazbot··on Inside the proton, the ‘most complicated thing you could possibly imagine’
OP assigned -3 units of charge to the electron, so all works out.
hazbot··on Ask HN: Anyone left software to study non-STEM subjects?
Love to hear you're still teaching a decade later - I'm starting my Masters of Teaching next week to become a math teacher!!

What do you think the biggest mistake that people who don't last as a teacher make?

hazbot··on Are you a “harbinger of failure”? (2015)
The paper is here https://dspace.mit.edu/handle/1721.1/111114 and is very accessible reading.

My takeaway is these ‘Harbingers of Failure’ have tastes not shared by the broader market, and so success only among the harbingers is unlikely to spread.

They also allude to an idea that overtuning tech products to early adopters is dangerous because they are possibly weird and unrepresentative of a bigger potential market.

hazbot··on A Mathematician's Lament (2002) [pdf]
How many plumbers feel Like most of the math they did was soulless and irrelevant, but don’t mind or even like that they got to do some art in school?
hazbot··on A Mathematician's Lament (2002) [pdf]
I read the first few chapters, then went off and just hacked on some math for the joy of it.

It was incredibly freeing for me at least to hear the message of ‘think deeply about simple things’ with the realisation I don’t care like I used to that there are other people are smarter and faster than me.

I recommend it.

hazbot··on Teaching Hopelessness to Kids of Color
Substack has been broken for me Firefox on iOS for a little while now.
hazbot··on The case for how and why AI might kill us all
Previous doomsday predictions must be wrong, otherwise we wouldn’t be here to say they were wrong.

But part of the reason the other doomsday scenarios were wrong is because people took them seriously and tried to mitigate the risks.

hazbot··on AWS Announces Open Source Mountpoint for Amazon S3
Fair point, defs should be mentioned by any serious article.

I have use cases where forbidding writes is a feature, and if it means more stability and performance it’s a trade-off that’s worth it to me.

hazbot··on AWS Announces Open Source Mountpoint for Amazon S3
I’ve been burnt by trying to use FsX as a mount-s3-as-a-readonly-filesystem. Flaky mounts, complicated workarounds for maintenance windows - if this lives up to the promise I can delete a whole module (and the cognitive overhead of reasoning about its state and behaviour) that we’ve written to manage a local disk to mirror an s3 bucket.
hazbot··on Windows needs to stop showing tabloid news
Every time I get a new windows device, I have to go hunting for the arcane registry settings to disable the start bar ads. It is really jarring when I use a relative’s computer with the default ad vomit.
hazbot··on US jet shoots down unknown object flying off Alaska coast
In Australia we use hydrogen in our weather balloons. It’s essentially a safety/cost trade-off.
hazbot··on Ask HN: Have you made a career move “down” on purpose, and how has it been?
Start living on the smaller salary now - see how it feels to cut the luxuries, squirrel away the rest into savings.

I’ve been to a colleague’s ‘demotion party’ from team lead to IC in another office - they had no regrets.

Be prepared for employers to be nervous about employing you - some will be worried about you being too big a flight risk because you might still have an open door to senior PM roles. So plan to manage that fear on their side.

hazbot··on Argentina's currency exchange black markets
In Australia we refer to ourselves as part of the “western world” - despite the geography being nonsensical!
hazbot··on The Shameful Decline of Scientific American
Also your approach is more honest than saying ‘keep science apolitical’.
hazbot··on There are infinite worlds to explore
I found the generation technique fascinating, but the images felt 'wrong' - I felt like I didn't know where to look to get an overview of the scene, and when I tried to focus on details it was like me eyes kept 'slipping off' because nothing would resolve itself.
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