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hotpockets

304 karma · joined August 26, 2008

my google mail account is tbsisan
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hotpockets··on Silicon Valley Guru Blasts Y Combinator Hype
We're just arguing different things.

You're saying value investing for startups is a suboptimal strategy. (I understand your point and read swan farming and found it highly interesting.)

I'm saying that may be true but that doesn't stop investors from trying.

Khosla is one of these people. He appears to have just stated he was.

Now maybe there are ulterior motives at play, and Khosla is lying about his aversion to superhyped startups.

Basically I'm saying investors have a distribution of frugality coefficients, and was asking: what does it look like if you plot "frugality" versus "investor quality". I would guess there might be a small relationship. Even if frugality is strongly negatively associated with quality, it is still true that high valuations will turn-off some quality investors. However, the important question is not whether you turn off some good investors, but, how many good investors do you attract, period. Thus hype may still be good.

hotpockets··on Silicon Valley Guru Blasts Y Combinator Hype
Khosla is simply stating the fact that some quality investors shy away from "hot/overhyped" investment opportunities. You can't argue with fact. However, some quality investors are also attracted to "hot/overhyped" startups. Which effect dominates?
hotpockets··on Black Swan Farming
Isn't there a simple solution to this problem? Bundle the unfundable ideas into a secretive spinoff. Say, call it YC BlackOps, or something. Keep it mysterious, like Google X Labs. If you do it right, it won't hurt the YC brand.
hotpockets··on Would you use this? A keyboard-friendly, social checklist app
Cool. An undo funtion would be nice. Like if you accidentally delete an item.
hotpockets··on Why publish science in peer-reviewed journals?
I was assuming that the article was suggesting a system that is similar to reddit, but with important differences. For instance, requiring real names and public voting records. Or, you could reduce a person's vote importance if they are voting on an article outside their area of expertise. There are probably other things you could do to.
hotpockets··on Ask HN: Best Practices on creating video for a startup?
This quora thread had a lot of great answers: http://www.quora.com/What-are-some-good-examples-of-startup-...
hotpockets··on YC Reject - We've been offered an investment to fund our Summer 2011 class
I was going to try something similar a while back. Perhaps a different persons perspective on a similar idea will stimulate your mind: http://news.ycombinator.com/item?id=925134
hotpockets··on Navigenics, 23andMe slammed in government report
Great, lets ban all information not approved by the state.
hotpockets··on My experiment with smart drugs (2008)
This means, like me, you have a Valine codon in place of a Methionine codon in your COMT gene at codon 158. This means the enzyme catechol-O-Methyltransferase which breaks down catecholamines like dopamine/norepinephrine has reduced activity and less stability, resulting in increased catecholamines in some areas of the brain.

I recommend downloading your raw data from 23andme and using the prometheus program from SNPedia. This is how I found out about this gene. This program is very raw but includes a lot more research and points you to the relevant papers.

Keep in mind, this information is all AFAIK, as I am just browsing this information casually.

hotpockets··on My experiment with smart drugs (2008)
Hey, you prompted me to look at the paper :). My understanding is that the study primarily looked at cognitive performance during an extended period of wakefulness (40hrs). Two doses of Modafinil (100mg each) were given during this period (the manufacturer recommended dose appears to be 100-400mg).

Modafinil improved the cognitive performance of Val/Val's (G,G)s across most of the tests (memory tests, mood tests, "Vigor" tests, reaction rate tests, well-being, fatigue, are ones i remember). Met/Met's (A,A)s did not see any statistically significant improvement on most of the tests. One test where there was a small effect for Met/Met's was in subjective well-being.

The study also looked at sleep recovery after the prolonged wakefulness. All participants entered deep sleep faster than normal.

90% of Val/Val's correctly identified their group (placebo vs. drug). 66% of Met/Met's correctly identified their group.

There were 10 people in the Val/Val group and 12 in the Met/Met group. But the small number of participants should be accounted for in the p-tests, as far as I know.

However, like you, I'd still try it given the chance. Regardless, lets hear it for our naturally increased dopamine!

hotpockets··on My experiment with smart drugs (2008)
Yes, you get about 570,000 single nucleotide polymorphisms (SNPs).
hotpockets··on My experiment with smart drugs (2008)
I used 23andme. I was lucky enough to be notified they were having a one-day sale a couple months ago. The sale price was $99 for the full reults, which is 80% off of their usual price of $499. The sale was on national DNA day.

There's at least a couple other similar companies out there, with more well known ones being deCODE and Navigenics. Recently these companies were getting in trouble with california health regulators for providing medical information without a doctor (I think that was the complaint, but I don't remember the exact reason). But the California complaint included 12 companies so there must be other companies as well.

hotpockets··on My experiment with smart drugs (2008)
One interesting thing I learned by getting my genes sequenced is that provigil would apparently have no effect on me. This would probably account for why a lot of people think provigil/modafinil didn't do anything for them.

About 25% of people of caucasion decent are (A,A) at rs4680, which is in the COMT gene whose enzyme degrades dopamine/epinephrine. Modafinil probably works by raising these catecholamines (at least in part). I haven't read it but the study is here: http://www.ncbi.nlm.nih.gov/pubmed/19037200?dopt=Abstract

hotpockets··on Competing with Greyhound: My NYC/Chicago Bus Venture
look at the megabus route map: http://us.megabus.com/routemap.aspx

Their rapid expansion across the midwest and east coast makes me think Megabus will likely offer soon a way to get from Chi to NYC. Perhaps the trip would take as long as the greyhound trip, I don't know. But its worth keeping an eye on. They have seemed to add routes about every 3 months or so. Connecting the midwest to the east coast would seem a natural progression.

hotpockets··on Ask HN: Good tool to visualize data?
Octave? (sort of an open source matlab)
hotpockets··on Ask YC: Publish the bubble list?
The benefit (if you were in the bubble list) being that your startup would have more recognition when posting.
hotpockets··on New Skate-Sharpening Method Takes Hockey by Storm
I think it provides a mild but noticeable difference. More grip on turns mainly, and slightly more glide. I can't comment on durability as I've only used it twice so far.
hotpockets··on Ask HN: How can I reclaim some of my commute time?
What makes your public option unviable?
hotpockets··on Ask HN: do you feel Google search result quality has gone down?
I hate searching google for technical jargon (and its worse the more technical the jargon is). Usually google just gives you a bunch of academic papers (in case you are wondering academic papers do not actually explain anything, they just use a bunch of jargon in a plausible way). Gee thanks. If you want I will think up an example.
hotpockets··on Ask HN: Tell me why a room-and-board-and-bandwidth incubator is a stupid idea
What sort of shape are they in?

I think the larger units are the most interesting. The chances of fostering success go up linearly with more entrepreneurs but there is also a much greater chance of having synergistic effects.

hotpockets··on HN: I'll run a marathon to build whatever you decide on tweet.in
Thanks for your comments, I agree that something automated is more efficient and robust. However, I was also thinking doing something manual might be a quick way to build and launch a site, even if it has poor accuracy. If you want to discuss it further, send me an email. Its in my profile.
hotpockets··on HN: I'll run a marathon to build whatever you decide on tweet.in
But how many ways can a rumor be stated? Say the rumor is someone got married: "did so-and-so just get married???". If you make a 100 sentence structures to look for could you reuse them for multiple rumors?
hotpockets··on HN: I'll run a marathon to build whatever you decide on tweet.in
There really aren't that many ways to say "I heard Jeff goldblum just died???". You could probably make a list of like 100 different ways and get good accuracy. In fact, question marks alone are a good indication the person didn't do any private verification.
hotpockets··on HN: I'll run a marathon to build whatever you decide on tweet.in
There is a real need for a reliability metric. For instance, a lot people recently tweeted rumors about Jeff Goldblum dying. Penalize those people. Other people actually were debunking the rumors, reward them. It will help quality to use an NLP grammar parser I believe. Every time there are rumors/scams on twitter you have a chance to improve your metric.
hotpockets··on We Need More (PayPal) Mafias
There is so much ambiguity in evaluating startups, investors rely too heavily on evaluation crutches such as being a previously successful entrepreneur. Sure there is some signal present in that metric but also a lot of noise, and I think more noise than most people admit (taking a kind of "fooled by randomness" thesis here).

It seems to me that second time entrepreneurs end up being bad for first time entrepreneurs because of it, funneling money to established successes. At least, thats the way it seems to me. A bit nepotistic. What we need is more opportunities for first time entrepreneurs, like YC.

hotpockets··on Bing Vs. Google Comparator
It would be cool if I could get an objective answer which results I prefer. Just give me the union of serach results in arbitray order, I will rank them, not knowing which is which. hen over time it could give me an objective measure of my preferences.
hotpockets··on Study: Potential criminals deterred by longer sentences
The ones with longer potential sentences

1) have received a larger gift, and would thus lose something larger. They may also experience a stronger desire to reciprocate this gift back to society.

2) can imagine a larger perceived injustice (compared to everyone else) if they are put in jail again. People judge things (including the size of punishment) through comparison, not absolutely. The key concept here is the punishment you would receive when "compared with others". If a person would get a larger sentence for an identical crime it offends there sense of justice and highlights the negative aspects of the punishment making it more salient in there minds.

I think my opinions above are still valid.

hotpockets··on Study: Potential criminals deterred by longer sentences
This analysis seems way too simplistic. These prisoners were given a gift of a shorter sentence. People don't like losing something they've been given and so work hard to avoid losing it. I don't think you'd see this effect if you just changed the laws and made prison sentences longer for everyone.

Only these people had the potential for a longer sentence, and compared to society at large, they knew they would be treated more severely. Thus the relative size of their potential punishment is larger then the rest of the people walking around outside. Nobody likes being treated harsher than the person next to them. That has got to have an effect on a person.

hotpockets··on Ask HN: How old were you when you got your first computer?
Me too. I loved playing parsec on that bad boy.
hotpockets··on [dead]
I have an all-ett. It is indeed uber thin and unnoticeable in my back pocket. It is sometimes so thin that I have a hard time opening it. I believe it will put an end to back pockets wearing thin and stretching out or growing holes. I like it.
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