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intenex

1,520 karma · joined January 26, 2011

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intenex··on Ketamine for the acute treatment of severe suicidal ideation
The truly amazing thing here is how powerful the placebo control was, even despite the fact that as someone who's done ketamine IV treatment before, it's pretty obvious when you're on ketamine and when you're not.

"At week 6, remission in the ketamine arm remained high, although non-significantly versus placebo (69.5% v 56.3%; odds ratio 0.8 (95% confidence interval 0.3 to 2.5), P=0.7)."

intenex··on MasterCard to open up network to cryptocurrencies
Wait - so why are other countries like Germany in the EU fine despite also not being able to arbitrarily issue their own national fiat currency?
intenex··on Amazon's anti-union site for its Alabama warehouse
If that's true...then why do you think Amazon is so afraid of/against them joining a union if it can't do anything?
intenex··on I got my money back from a scammer by contacting his mom on Facebook (2016)
^^ Eating animals. Firmly convinced we're on the wrong side of history on this one - when the world finally stops doing it en mass, either because clean lab grown meat has become economically more viable or environmental concerns are too overwhelming, etc., very convinced we'll look back on it as a horrific practice just as we might slavery today.

Aside: this thread escalated quickly from scamming Apple gift cards on reddit

intenex··on Teaching Rats to Drive Tiny Cars
"Just like us humans, learning to drive and navigate seemed to have a relaxing effect on the rats. In a control experiment, they found rats had higher levels of cortisol when being driven around in remote-controlled cars than when they were allowed to steer themselves."

From the futurism post https://futurism.com/the-byte/scientists-rats-drive-tiny-car...

Seems like a terrible control imo for me to say driving intrinsically has a relaxing effect. A better control would be rats doing nothing vs rats driving and seeing if the rats doing nothing were more stressed than the driving rats, meaning the driving rats were actually lowering their baseline stress.

In this experiment the control of being a passenger in a terrifying vehicle moving all by itself with no autonomy or control over the situation can quite likely be the thing causing elevated stress, rather than rats driving depressing levels of stress. Imagine if someone suddenly strapped you into a bubble that started moving by itself and you have no idea why this is happening, no control over the situation, or where you're going or what's going to happen to you. Stressful af. Hell, people get stressed just being in the passenger seat watching someone else drive.

The vast majority of people prefer having autonomy and control over their own motion vs being helplessly navigated by someone else you don't know/trust with zero context and no idea what's going on. A little misleading if this reflects the actual study.

intenex··on A Prison Lifer Comes Home
The article directly addresses the idea that "Being 17...doesn't make you less culpable."

"Of just over 200 released, six have faced new charges, but only one has been convicted of a new crime, contempt. That’s less than a 3 percent recidivism rate. “When you’re looking at the percentages of the guys who’ve come back in court, and compare that to our overall, which is around 40 percent, you really know you’ve done a good job,” Johnson said.

That outcome supports a theory the U.S. Supreme Court first advanced in 2005, when it outlawed the death penalty for juveniles. The Court took stock of “evolving standards of decency,” as well as a growing body of neuroscience suggesting kids’ immaturity makes them less culpable than adults. It also emphasized that kids, more than adults, are amenable to change. The low recidivism rates likely also reflect the reality that criminal behavior declines dramatically as people age out of their teens and early 20s."

There are a million things incredibly unwise things I would have been far more likely to do at 17 than 27 now - I imagine this is a trend that will continue to likely progress for me individually, and I also imagine this isn't a phenomenon singular to myself.

The shockingly low recidivism rate seems to empirically support this notion as well, particularly when contrasted with the general recidivism rate. If these juvenile offenders were just as culpable as anyone else when they had committed their life sentence crimes, presumably their recidivism rate should be similar. 40 percent for the general population and 3 percent for this cohort so far suggests otherwise.

intenex··on 94k Bitcoin (1B USD) transferred from unknown wallet to unknown wallet
Unknown meaning the owner of the address is unknown
intenex··on What Happened to the Guys Who Invested Their Life Savings in Cryptocurrency?
About as much of a massive pump and dump as the stock market, yeah https://www.macrotrends.net/1319/dow-jones-100-year-historic...

Tbf, way smaller tbh, but the pump shows no signs of decreasing over time, so we'll probably get there in the end. Crazy right

intenex··on SAT to Add ‘Adversity Score’ That Rates Students’ Hardships
As someone who went to Harvard, I'm pretty sure there are a lot of extremely decent universities that all basically provide the same quality of instruction. People just get unreasonably hung up over the 'best' schools, but there are easily at least like 100+, if not several hundred, that provide easily roughly the same educational experience as far as I'm aware.

The peer group may definitely dramatically different from what I can tell, but if you're a serious student and there for the learning above all, very straightforward to get into a school that will teach you just about anything you could learn at Harvard or any other Ivy League or similarly 'elite' school.

intenex··on Twisted graphene has become the big thing in physics
Fairly shocking to me that Yuan Cao received literally a single glancing mention here, but he was clearly the one who actually made the pivotal discovery, and is the first author on the Nature paper (https://www.nature.com/articles/nature26154), and was the one named to the Nature 10 in 2018 for his discovery.

Really mind boggling that this entire piece focuses all the attention on his supervisor and almost neglects to mention him at all.

intenex··on Single-dose propranolol tied to ‘selective erasure’ of anxiety disorders
Even having read the article, I thought your chosen quote was excellent, helpful, and much appreciated. Thanks!
intenex··on Show HN: Learn C and its lower levels interactively, in the browser
This is basically the coolest thing ever huge insane thanks for putting this together man, you are a true hero
intenex··on How Clara Labs (YC S14) Is Using Humans to Build AI
Would love to integrate the ML and context aspects of Clara into our existing assistant team. Curious if that's something that's doable, or if it's just a package deal of their trained operators + AI.

But yeah, basically awesome and everything we'd need. Being able to go even more in-house and specialize our personal assistant and equip them with augmented capabilities here would be even more awesome.

intenex··on Anxiety and Depression Are Symptoms, Not Diseases
Agreed 100% here. I was chronically suicidal and depressed from 8th grade all the way through my first semester of college at Harvard. Someone jumped off a building halfway through that first semester, and ever after, I couldn't stop thinking about killing myself. Knew I'd unequivocally off myself if I stuck around, so it finally provided the impetus for me to drop out, travel around the world, get a Thiel Fellowship, and now be surrounded by the most amazing group of friends, family, and coworkers, and to be working on something I truly find meaningful.

Haven't been depressed or suicidal in the slightest since I came out here to SF and started living an autonomous life on my own trajectory half a decade ago. Was 100% circumstantial and situational for me, took zero drugs and professional therapy didn't do anything. Changing my life circumstances did everything.

intenex··on Anxiety and Depression Are Symptoms, Not Diseases
Nope! I was chronically suicidal and depressed from 8th grade all the way through my first semester of college at Harvard. Someone jumped off a building halfway through that first semester, and ever after, I couldn't stop thinking about killing myself. Knew I'd unequivocally off myself if I stuck around, so it finally provided the impetus for me to drop out, travel around the world, get a Thiel Fellowship, and now be surrounded by the most amazing group of friends, family, and coworkers, and to be working on something I truly find meaningful.

Haven't been depressed or suicidal in the slightest since I came out here to SF and started living an autonomous life on my own trajectory. Was 100% circumstantial and situational for me, took zero drugs and professional therapy didn't do anything. Changing my life circumstances did everything.

intenex··on TldrLegal – Software Licenses Explained in Plain English
Cunningham's law hard at work.
intenex··on Gmail was down
I think that one's pretty easy: Why is it down? Technical hypotheses, discussion of past history of outages, etc.
intenex··on Anti-ageing compound set for human trials after turning clock back for mice
Boom. This was a great rebuttal, I just needed to say that.
intenex··on The Feynman Lectures on Physics, Volume II
Why didn't this just link to http://feynmanlectures.caltech.edu/?
intenex··on Single-Sex vs. Coed: The Evidence
Aside from all the other points, I'm curious to see further longitudinal data on the comparative success of these students once they enter college compared to their peers at college.

Further, it'd be interesting to see their eventual success against those who went to the coed schools.

It'd also be interesting to run a self-assessment of the single-sex students vs the coed students asking them a broad array of well-being questions, e.g. their happiness, level of fulfillment and satisfaction in life, etc.

Interesting starting point, but like pointed out flawed to say single-sex schools are better overall purely based on this one metric. The only thing that can be said here is that single-sex schools drive greater admission to colleges than coed schools in Seoul, given the way these schools are administered there.

Things that definitely need to be addressed - what are the differences in the coed vs single-sex schools these people go to? Are the single-sex schools taught differently at all? And if so, how? Why does Seoul have a single-sex vs coed separation in the first place?

intenex··on A Prediction: Bitcoin Is Doomed to Fail
"They will fail, because money that is not issued by governments is always doomed to failure. Money is inevitably a tool of the state."

How about gold? Bitcoin can just as easily be seen as a limited commodity as as currency. It's even mined :).

intenex··on What It's Like to Fail
Wow, that wasn't the most cynical thing I've ever heard at all.
intenex··on Are You A Typing Hacker? Prove It
All I want to say is I got to level 27 on expert mode and I'm quite proud of this fact.

http://www.youtube.com/watch?v=WDpF3qymPqA

intenex··on Starting an Airline
Where did you get those numbers? http://www1.salary.com/Emergency-Medical-Technician-Salary.h...
intenex··on My Friends and I Bought an Island
For now*. Don't forget the artillery for imperializing neighboring islands.
intenex··on My Friends and I Bought an Island
He did it for a higher calling -- namely having a penguin as a pet. Maybe if you make that your justification too your wife will jump on board, so to speak.
intenex··on My Friends and I Bought an Island
Hey all - co-owner here with Tynan. He tried to reply to all your comments but you guys left so many he got throttled by HN and now can't post. Shame on you all.

Just kidding - but really, he's throttled atm. He'll be back to reply to posts when he can!

intenex··on My Friends and I Bought an Island
Each, 4 figures.
intenex··on My Friends and I Bought an Island
Hah Tynan got throttled by HN for posting too many comments too quickly. I'm also a co-owner of the island:

1. Yeah, we definitely have plans for structures -- yurts, we're actually thinking. 2. Hmm, haven't explored that option. Not sure. 3. Yep - tentatively 5 guests per each owner at a time. 4. Yeah food would definitely be fantastic. 5. We don't have helicopters yet unfortunately, but when we're mad rich sure :)

intenex··on My Friends and I Bought an Island
Thanks for the heads up! We'll def be sure to get on that and get some basic first aid training across the board + med kit on site. Any other advice/tips we should be aware of?
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