issa

Our metabolism doesn't change in the technical sense, but in the popular sense of the word "metabolism" people absolutely slow down. At 20, missing a night's sleep wasn't even that big a deal. At 50 it is essentially impossible. I don't know what the underlying mechanisms are, but that's what people mean when they (incorrectly, it seems) say "metabolism".

I could not agree more. I feel like there is constant push back against attempts at decreasing the total number of blocks.

Agreed. But there are many examples. Take food production, which is one of the largest environment killers. Keeping people alive in space will involve novel food producing technology that might help stop people on Earth from destroying forests for grazing land, etc.

OutVoice | DevOps and Backend Engineer | California based REMOTE company. Worldwide is fine. | Full-time or flexible.

OutVoice is a startup that helps publishers pay and manage their freelancer workers. Our stack is terraform/kubernetes, mysql, nodejs/express, typescript.

Email jobs@outvoice.com and say hello. Passion around journalism, freelancing, or content creation more important than resume or specific experience. The salary range is going to be more in line with a junior position, but there is equity and benefits, and lots of room to grow.

https://outvoice.com

Not destroying the Earth seems pretty critical to everything. Getting the technology to travel to and live on Mars would help that goal. Think of the benefits things like generating power in space and moving heavy industry off of Earth would create.

Agreed. But Venus might be better. We'll see.

It is a known that eventually a planet killing asteroid will hit the Earth (again). We just don't know when.

But, more importantly, it is a misconception to think that the people GOING to Mars will have their lives improved. Life on Mars will take a very long time to become as good as life on Earth. But the tech developed to make living on Mars possible will help people on Earth.

I am definitely not underestimating how great Earth is. But we will learn how to make other places comfortable too. The trick is to remember that technology will improve. Living in a tin can on Mars would suck. Living on Mars with fusion power, biological enhancement, nanobot construction, etc, etc, etc is an entirely different story. Personally, I'd love to live on a ship. I'm aware I was probably born 100 years too soon.

Expanding human life to Mars (and the entire solar system) is a fantastic goal for humanity. Better than just about everything else we could do. To accomplish it, we will solve many problems along the way. I would much rather we advance our technology in the pursuit of Mars than in the pursuit of weapons of war.

I would hesitate to call this really bad advice, because it would be correct for some people at a certain age or point in their life. But, based on the OP, it doesn't sound like what is called for. It really depends what kind of job you want.

even better: https://en.wikipedia.org/wiki/xvx

This sounds very strange to the uninitiated, but I grew up in a part of the punk music scene that was rebelling against drugs and alcohol. As someone who has never had a drink, I've never seen the appeal, and I always wonder why more people don't give it up. https://en.wikipedia.org/wiki/Straight_edge

My initial thought was "wow, this would have been cool when I was a kid, but now I just need to look up!"

And then I actually went to the site. Holy crap. It's really incredibly well done. Kudos!

Lots of good advice in this thread. I will just add that you have NO IDEA what will happen in the next year or decade. Life gets different as you get older, but not all of it is bad.

Read in the voice of Marvin, The Paranoid Android

I just mean that in a perfect world (or even one with a normal health care system), my doctor should have reached out to me and said "hey, there is a new class of drugs that might help you". Instead, I had to hear about it on my own, read a bunch of studies, explain what it was to my doctor, then go through a ton of insurance back and forth to get them to prescribe it.

I think it is fair to say that there is a variety of reasons why people are obese. Some people certainly eat out of boredom, for emotional reasons, taste, etc. But there are people who also feel hungry all the time. Those people will benefit. Others may as well.

No, not at all. More like it takes away your hunger. You could still overeat, but you won't do it because you feel hungry.

I feel like I could have written this myself. And I am also fairly certain that someday the cause(s) of this constant hunger will be identified and we'll someday be spared of people criticizing our "willpower".

So much to say on this subject but will try to keep this concise. This class of drug is absolutely a miracle cure but with some footnotes.

1. The problem it solves is obsessive appetite. I used to read about people saying things like "oh, I was working so hard, I forgot to eat" and I wondered how that was even a possible thing. This takes certain types of people from being constantly hungry to what appears to be "normally" hungry. If you are overweight because you are CONSTANTLY hungry, even right after you eat, this is the solution for you.

2. To everyone else, the people who just really like donuts or whatever, I am not sure what this will do for you. I don't mean it won't help, I just literally mean I have no idea, because my personal experience doesn't speak to this.

3. Intermittent fasting. Because it's impossible to talk about dieting without someone bringing this up. I think IF is wonderful, but, for people like me who have appetite issues, these drugs are helpful for following IF. But I would say the two are not related--they solve different problems.

4. I had zero side effects, but had to jump through an INSANE amount of hoops to get this stuff.

A friend with MTV made VHS copies for those of us without cable. So good. And Madness!

I am 50 years old, a science fiction fan, and an amateur follower of actual science. Generally speaking, the sci-fi authors are the best at making predictions. https://archive.nytimes.com/www.nytimes.com/books/97/03/23/l...

This is not the typical definition of "highly processed foods". I'm curious what you do eat.

2 things:

- everyone is different

- there are plenty of low-carb, high-protein vegetarian sources (see: tofu)

oh yeah. I think that was an AR conference at American University? Fun!

oh man. I appreciate the sentiment, but the only music these days is jamming with my daughters around the house.

That's awesome. Of course I remember that email! haha. Hit me up sometime and we can talk startups, tech and hardcore. You probably know my co-founder's publication... The Hard Times?

I was in a band called Good Clean Fun. In 2000 we played in Dundee, Edinburgh, and Glasgow. Definitely a small scene, but we had a GREAT time.

Also a common misconception that hardcore punk bands only play power chords. A lot of bands are playing barre chords and hitting all the strings (imagine!). I learned most of the songs in the examples that way--whether the original guitarists did or did not, I don't know.

Full disclosure, I am a self-taught, punk musician with minimal knowledge of music theory. But most hardcore punk songs are just pop songs sped up, so I don't see how one can have a chord progression and the other can't.

Ha. I am indeed. And this is not the place I usually expect to discuss hardcore!