jrowley

I’ve been force carbonating since this summer. Have a few 2 liter bottles in the fridge with cold water at all times. A great, cheap, healthy alternative to other beverages like soda or beer.

Trial recruitment is definitely one the hardest parts of running a successful trial. With rare diseases reaching out with existing patient groups is one of the most successful recruitment mechanisms.

Jira now has OpsGenie so you don’t have to cobble anything together, in theory.

The lengths a person will go to to procrastinate on starting a run ;) very impressive!

These are relatively new restrictions - have been rolling out since this fall. https://support.twilio.com/hc/en-us/articles/1260800720410-W...

I've found sending from toll free numbers like 1-888 reduced filtering also. Only costs like a dollar or 2 a month extra.

I would definitely layout all the options for the client, including an option which is abandoning your software and migrating to / developing a new option. Putting that other option on the table will make whatever you propose seem like the obvious choice.

Have you considered sending them a pig fetus? Maybe they would respond?

For those who don’t get the joke:

https://www.cnbc.com/2020/06/15/ex-ebay-employees-sent-blood...

I know you said avoid AWS , AWS SES is really pretty simple and cheap. If budget is any concern might be worth investigating it. You can have it generate smtp credentials and use them with whatever client you want.

Amigo means friend in Spanish. No more of a made up word than academy.

You should ask if he has discussed this stance with a doctor he trusts and encourage him to do so.

Curebase (YC S18) | Engineering Manager, Technical Solutions Engineer, Senior Full Stack Engineer | Remote (UTC-5 to UTC-8)

Modern Clinical Trial Software

At Curebase we run distributed clinical trials that reach participants everywhere and enroll them in local clinics. Our software platform replaces eClinical tools, stores data in the cloud, and supports modern study designs that combine in-clinic and at-home data collection.

We just raised our Series A in May and are growing rapidly (currently 9 engineers + Head of Engineering). On the engineering team we are hiring for an Engineering Manager, as well as Technical Solutions Engineers and Full-Stack Senior Software Engineers. Our stack is Node.js, Typescript, React, Express, Postgres, powered by AWS ECS/Fargate/Docker, RDS, etc all configured via Terraform.

More info here: https://www.curebase.com/site/careers

Exactly. Does bussing help the individual or simply get them out of your way?

Sometimes returning people to their support networks in other states can be a solution, but “banishing” doesn’t sound legal or ethical.

But you can’t move these individual’s support networks also. Their friends, family, doctors. They might not have a permanent living space, but they may have a city they grew up in, a place they call home.

A salary of 200k still puts you in the 95th percentile in the US. Don’t be too sad!

I like how much you are focusing on developer focus here! I guess you need to compare this against something else for it to better. At my workplace, we were originally really small, just 3 or 4 engineers, so have a code-review specific channel where all members of the channel get notifications from github for ALL pull requests. As the size of the team increases (closer to 10 engineers now), I think the value from this channel is kind of decreasing, since there are fewer conversions happening in it. So this tool helps solve that problem.

I really appreciate how this reduces notifications for engineers not involved in the review.

> FDA approved Tembexa under the agency’s Animal Rule, which allows findings from adequate and well-controlled animal efficacy studies to serve as the basis of an approval when it is not feasible or ethical to conduct efficacy trials in humans.

How doesn’t this make sense?

If you looked at the timing of his trades combined with his success, that alone could be suspicious, which could lead to a quick investigation determining he was married to the insider employee.

They were probably developing the app themself and forgot they included the information in a test card or something?

The actual cost of the drug is only part of cost… malpractice insurance, accepting some risk for off label impacts price.

You could run into some limitations, since as far as I know there is only 1 self hosted runner configuration for a given organization. You can’t for example request a specific workflow run on a specific class of self-hosted runners or something like that.

Github also support self hosted runners! We are using those for certain jobs at organization. Very convenient.

https://docs.github.com/en/actions/hosting-your-own-runners/...

Whenever this happens I create a filter and skip the inbox from that sender.

I believe hasura uses polling under the hood to accomplish subscriptions, right?

Can you open a new account and open a support ticket on that? What a nightmare situation. Wishing you the best of luck.

He totally sounds like an independent contractor, definitely has a lot of control over his work. Most definitely not an employee of Amazon or a shell company who’s only customer is Amazon.

Re 1) Maybe you could cache with cloud front?

I have a very intelligent, kind friend who lives alone, got deep into meditation during covid, started hallucinating / getting increasinly paranoid, and ended up hospitalized for a couple of weeks and diagnosed with schizophrenia. She is doing better now but will almost certainly have to drop out of school. That's not to say meditation is a bad thing, or should be avoided, but it isn't without risk or harmless necessarily either. If it can do so much good, what's to say it cannot also do bad. The mind is a powerful thing.

Curebase (YC Summer 18) | https://www.curebase.com/site/careers | Senior/Mid-level Full Stack Software Engineer | San Francisco or Remote (with good tz overlap) | Full-time

Curebase is a fast growing startup pioneering the space of distributed clinical trials. We have a small but mighty engineering team that builds the platform that powers our clinical trials, including submissions to the FDA involving fighting COVID. Our tech stack is full stack javascript (quickly moving to typescript), graphql, react, node.js, postgres all on AWS configured via Terraform. This is a high impact role at a small company. You could have an outsized impact on the product and engineering culture at the organization. I'm the head of Engineering at the organization and my email is in my profile if you have any questions!

Honesty, I’ve been using LastPass for years and lately the chrome and Firefox extensions have been really buggy for me. Especially the chrome one. So I’m not sure it’s nefarious.