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llccbb

244 karma · joined January 12, 2017

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llccbb··on Mapping Australia’s Coast with Landsat Satellite Imagery
RemotePixel.ca[0] has my favorite interface for discovering Landsat 8 images.

[0] https://remotepixel.ca/projects/satellitesearch.html

llccbb··on Mapping Australia’s Coast with Landsat Satellite Imagery
Quick plug for a site that shares beautiful Landsat desktop wallpapers. https://landsat365.org
llccbb··on Ask HN: Do you keep a developer diary?
Have you every considered using Jupyter Notebooks[0] or is the execution of code not so important?

[0]http://jupyter.org/

llccbb··on Ask HN: How can I do social good through programming?
I have posted this before, countless times, but techies who want to volunteer their skills and knowledge to advance the democratic process should think about joining the PROGRESSIVE CODERS NETWORK[0]. They are a non-profit that helps organize and direct volunteer coders, programmers, designers into open-source political projects. They are about connecting and facilitating projects, not dictating what projects should be. They are party-neutral, but seek to empower the people and provide tools for running successful campaigns and being engaged as a citizen.

If you can take away the need for millions of dollars to run a campaign then policy makers aren't beholden to the few wealthy supporters that helped get them elected.

They help connect volunteers to projects that range from building an open-source voter database to an Uber-like app that helps the mobility-limited get transportation to vote. They are extremely transparent and always interested in growing the network. Many members of the network are engineers, product managers, or independent coders.

[0]http://progcode.co

llccbb··on Beware of Transparent Pixels
Each pixel is defined by 32 bits -- 8 R, 8 B, 8 G, 8 A. Even if alpha is 0, there has to be information stored in Red, Green, Blue. There can't be "no information", because then a pixel is not defined by 32 bits of information. There is always a "color" (RGB values) for transparent pixels. Some editors will set the RGB values to 0 or 255 when fully-transparent pixels are saved/output. Others don't.

As the author mentions, certain resampling algorithms might be naive or plain ignorant about how to resample images with potentially transparent pixels. Should transparent pixels not count to the final pixel? Should all pixels be averaged? Should the output pixel be the median or mode value? If the image is being resampled to 1/3 its size the resampling can be very cheap if only the middle of the 3x3 pixel cluster is selected as the output value.

llccbb··on Mass Extinction and the Structure of the Milky Way (2013)
Interested parties should also look at the work of Dr. Adrian Melott[0].

[0] https://scholar.google.com/citations?user=GWB114EAAAAJ&hl=en...

llccbb··on The U.S. wind industry now employs more than 100K people
As someone who is working with global powerplant data I can say that the US is the global leader. It is not perfect, but it is miles ahead of 170 other countries.
llccbb··on Google Earth Redesigned
Google has been one of the largest purchasers and schedulers for aerial photography over the past 5+ years. Traditionally aerial photography uses airplanes as the flight system.
llccbb··on Company sued EFF over “Stupid Patent of the Month;” EFF now flips the script
Someone really should patent "a method for identifying and litigating on patent infringement".
llccbb··on Apple has biomedical engineers developing sensors to monitor blood sugar
I don't have a link available, but I will try to describe it.

Insurance company A needs to help with a wide variety of prescription needs -- cholesterol management, heart disease, kidney disease, cancers, MS, diabetes. Insurance company A negotiates with pharmaceutical companies B, C, and D for how much A will pay for any drug and what copay A will charge to the insured patient.

Pharma B makes a deal to ensure that their diabetes drugs are on tier 1 or preferred status (most likely to be approved/used/paid) in exchange for a very good deal to the insurance companies on the price for each prescription and a lower tier for their cholesterol drug. The agreement also states that all other diabetes drugs (insulin, let's say) will be tier 3 or need prior authorization. This is a contract that might last a year or 5 and is not public.

Company C makes a deal to get their MS drug as the only reasonably priced option in exchange for basically giving away their foot fungus drug. The insurance company is happy because every foot fungus prescription is pure profit. Company C is happy because they are they only game in town for MS treatments on that insurance provider.

Pharma D wants to get their insulin at a higher tier so that patients can afford it and not buy out of pocket. But Pharma B already has an agreement that all other insulins will be tier 3 or lower, so Pharma D is locked out of that insurance company.

The current health insurance and prescription system in the US __heavily__ favors large pharma companies that can negotiate on multiple grounds and leverage competing health interests. Small pharmas that offer a singular stellar product have a tremendous fight to even get past prior authorization.

llccbb··on Apple has biomedical engineers developing sensors to monitor blood sugar
I think alternative delivery mechanisms to injection are a feature. Ask any diabetic if they would like less needles in their bodies. There is work and patents on adjustable dose inhaler systems, but its never going to be a basal insulin that is being delivered. It's prandial.

The lung cancer concerns come from the only previous inhaled insulin Exhubra, which was literally vaporized insulin solution and offered no pharmacological benefit over injected insulin. The two instances of lung cancer in the 12(?) years of Afrezza testing occurred with patients who were smokers.

I'm not saying that Afrezza is the greatest invention ever, but it is a substantial step up from other mealtime insulins in my opinion.

llccbb··on Apple has biomedical engineers developing sensors to monitor blood sugar
I am certainly not defending the article, but here is my take from living and being very close with a type-1 diabetic. The holy grail of __treating__ diabetes is technology that helps maintain excellent blood glucose control. Diabetes Mellitus (T1) is not a curable disease right now except through pancreas transplants. Diabetes is therefore a disease that has to be treated. The treatment for diabetes is personal, non-uniform, active, and adaptive. Every ingestion of food or liquid affects your body and needs to be considered.

Diabetes is a disease that needs its symptoms to be monitored and managed at a high granularity. Both monitoring and managing blood glucose can be really invasive though, with needles and finger-sticks causing extensive scar tissue development. Minimally invasive glucose monitoring technology that generates high-resolution time series data (such as Dexcom systems) literally transforms the way that people can manage their disease. Going from glucose reading every 6 hours (test strips) to every 5 minutes (CGM) is life changing. Monitoring that is non-invasive is the next technological step.

The holy grail for treating diabetes should actually be stabilized monomeric human insulin. Afrezza[0] is exactly that, and inhalable no less. The company that makes it just can't break through the insulin cartels and insurance-pharma exclusivity, so they are having a hard time. They did what was unachievable for 100 years though, and they are amazing chemists.

[0] https://www.afrezza.com/hcp/afrezza-action-profile/

llccbb··on Host Your Own Content
There is lots of discussion about hosting static assets like images or videos, where that _asset/media is the content_. I am wondering what the best self-hosting solution is for these cases.

Let's say I am a photographer and I want to create or share some image galleries. Each image is big, about 10 MB and there may be hundreds of these images (less than 1000). They have a very permissible license, and I want them downloaded and used as wallpapers, for instance. I want the webpage traffic on my site (over flickr) because I want to drum up business and recognition for myself, but I don't want to risk my site going down under hug of death situations. Low cost solutions are ideal because this is a side project.

Is it best to host the main site on a single server (DO droplet) and kick the heavy lifting of image transfer to someone like imgur? What is the cheap and robust solution to this sort of problem?

llccbb··on Ask HN: What medical datasets do you need?
Blood glucose levels as time series from continuous glucose monitors with additional tagged data like food intake, exercise, and sleep. Each record needs the obvious human-data like sex, age, weight, nationality/ethnicity, type 1 or type 2 diabetes.
llccbb··on Ask HN: How does HN maintain quality vs. Reddit and the media at large?
Posts/comments that are pure images aren't tolerated.
llccbb··on Show HN: Making a huge Google Map
My first thought too. My guess is Google won't pounce until someone tries to monetize or offer it as a service.
llccbb··on SoundCloud needs more money, or it may sell at a fire-sale price
I have been rabidly downloading and archiving my favorite podcasts that post on soundcloud. I have two fears. The first is that they may become lost forever due to lack of interest/awareness of the creators. The second is that the creators take this opportunity to lock old episodes behind a paywall.

I would love to see the Internet Archive put some muscle behind saving all the wonderful content on soundcloud.

llccbb··on Orion Ubuntu Laptop Review: The Powerful MacBook Pro Alternative
This seems like a "MacBook Pro Alternative" in that it is a "Laptop computer".

>Design wise there’s nothing spectacular on show here. It’s almost but not quite ‘generic laptop’ but that’s fine.

>There was a point where I was considering digging out a mouse to help drive the OS.

llccbb··on Ask HN: Is there any IMDB for softwares?
makerbase.co[0] isn't exactly what you want (reviews of software), but I think it is closer to IMDB than anything else. It tracks and databases contributors to projects, much like IMDB tracks writers, actors, etc that contribute to media.

[0]http://makerbase.co

llccbb··on Curing Diabetes with a Low Carb Diet
Type 2 diabetes is a lifestyle disease. Changes in lifestyle can reverse the disease. Coupled with early intensive insulin treatment, exercise and diet is __the known cure__ for T2. The current (pharmaceutical) standard of care in America is to subject the patient's body to further stress at the expense of vital organs.
llccbb··on Your CV as an Infographic (using LaTeX)
Nice graphic and template. I don't think this is a CV, but maybe there is a European/American difference in what that means.
llccbb··on Show HN: $2 incremental pricing logo project
Making money at O(n^2 + n)
llccbb··on Cloud-Based Services Every Tech Department Should Be Using
#4 is CloudFlare
llccbb··on Ask HN: What are your favorite tech podcasts?
I've been enjoying the podcast Courtland!
llccbb··on Fasting diet 'regenerates diabetic pancreas'
The insulin cartels are real!
llccbb··on Ask HN: How can I volunteer my software skills online?
I have posted this before, countless times, but techies who want to volunteer their skills and knowledge to advance the democratic process should think about joining the PROGRESSIVE CODERS NETWORK[0]. They are a non-profit that helps organize and direct volunteer coders, programmers, designers into open-source political projects. They are about connecting and facilitating projects, not dictating what projects should be. They are party-neutral, but seek to empower the people and provide tools for running successful campaigns and being engaged as a citizen.

If you can take away the need for millions of dollars to run a campaign then policy makers aren't beholden to the few wealthy supporters that helped get them elected.

They help connect volunteers to projects that range from building an open-source voter database to an Uber-like app that helps the mobility-limited get transportation to vote. They are extremely transparent and always interested in growing the network. Many members of the network are engineers, product managers, or independent coders.

[0]http://progcode.co

llccbb··on Dole Food Had Too Many Shares
Naked shorting is practically legal, and basically unenforced. The seller only has to claim that there was "good faith reason to believe" that shares could be reasonably acquired within the settlement period (3 days). See Goldman Sach's infamous "Easy to Borrow List"[0].

Coordinated naked shorting attacks are real and legal. Flood the market with false shares and tiny lots of low-asks. Rapidly drop the price down to capture the easy stop-losses that retail investors might set. It is fool-proof because you know those shares can be obtained at a certain price (hedge-funds and market-makers can see the stop-losses). As soon as you acquire the stop-loss shares, pull off the selling pressure and use the shares just obtained to fulfill the short-contract. There is no borrowing.

[0]https://www.deepcapture.com/2015/07/goldman-sachs-internal-m...

llccbb··on Dole Food Had Too Many Shares
The problem with naked short selling is the ability for rampant, cheap, and extremely profitable manipulation to cause "artificial" price-drops. There is basically no penalty for failure-to-delivers and companies share price can be gutted while no real shares have been traded.
llccbb··on Long-awaited mathematics proof could help scan Earth's innards
I saw a talk by Maarten de Hoop, who is one of the seismologists interviewed in this article. The talk centered around designing the structure of __huge__ matrices to help solve immense systems of equations that were constantly being mutated with more input data. Most of it went over my head, as it was a talk also given to the mathematics department, but I was astonished at the ingenuity of the computational seismology community. They were designing and manipulating matrices into complex fractal forms that made these unbelievably complex reduction operations fairly simple and mathematically favorable.
llccbb··on ACLU hires Bernie Sanders organizers to build platform to mobilize citizens
I have posted this before, but techies who want to volunteer their skills and knowledge to advance the democratic process should think about joining the PROGRESSIVE CODERS NETWORK[0]. They are a non-profit that helps organize and direct volunteer coders, programmers, designers into open-source political projects. They are about connecting and facilitating projects, not dictating what projects should be. They are party-neutral, but seek to empower the people and provide tools for running successful campaigns and being engaged as a citizen.

If you can take away the need for millions of dollars to run a campaign then policy makers aren't beholden to the few wealthy supporters that helped get them elected.

They help connect volunteers to projects that range from building an open-source voter database to an Uber-like app that helps the mobility-limited get transportation to vote.

[0]http://progcode.co

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