maxk42

A calorie measures the heat released by setting the food on fire, which is not how your body metabolizes food. It's a proxy. You should be measuring the ATP yielded by eating food. For example, a molecule of glucose yields 32 ATP when metabolized, yet a molecule of DHA yields 136 molecules of ATP - nearly twice as many as predicted by the "calories" proxy. However, in the absence of oxaloacetic acid (as when the liver is using the majority of OAA for gluconeogenesis during intense exercise or when limiting carbohydrate consumption) your cells have to use a less efficient series of metabolic steps to produce energy and only end up yielding 22 ATP for DHA metabolism. I eat 3500 calories a day and don't exercise yet I'm losing about 2 pounds of fat per week.

CICO was never law.

And g+ / g-

You're making the assumption that artificial sweeteners solve the problem of weight gain. The studies that have been conducted so far show only a minimal impact to body composition by switching from sugar to artificial sweeteners. There are more mechanisms at play than are presently understood.

Forgive me for the incomplete reply, but I looked this up last week and one molecule of fatty acid (in this case DHA soecifically) generates 136 molecules of ATP. This makes fat roughly 2x as energetic (from the standpoint of our bodies' metabolism) as the heat measured from burning it (calories) would suggest. Despite this fact, and the fact that I've been eating roughly 3500 calories per day without exercising, switching to a high-fat, low-carbohydrate diet has lead me to lose 10 lbs over the past three weeks. Clearly there's a lot more to metabolism than is even documented in this lengthy article.

I have preferred Dell machines almost exclusively for about nine years. Then in this past December my Dell daily driver went blank in the middle of playing a YouTube video, never to boot again. I bought three replacements (Inspiron line) back to back and each one failed in turn within a week. Finally, frustrated beyond all belief I tried an HP. It had less RAM and no number pad, but otherwise has served adequately for nearly a year now. Unfortunately, after sinking $3000 into new computers in less than two weeks I've had to swear off of Dell. They just don't have the quality control I'd previously been accustomed to.

Sad to see this is the lowest-voted comment here while simultaneously people above in the thread are replying with things like "I'm not sure how I'd provision servers without something like Docker" thereby proving your point.

The vast majority of comments have nothing to do with containerization which is the purpose of Docker and unfortunately Docker just isn't that great at it. Meanwhile, they use it for configuration and in lieu of system administration which has multiple drawbacks and does indeed waste resources.

I'm sure I'll be downvoted as well but thought I'd comment so you don't feel so alone. Keep doing things the right way.

My wife was 40 when we had our first and 43 when we had our second. Both healthy and bright. No windows have closed, but if you really feel like you can't then you should consider adopting.

If you file a lawsuit against your critics then you're not a scientist.

That's what 'n' is for. It also doesn't overwrite the 's' keybinding which is already used for substitution. I don't see the point of this plugin for people who are actually familiar with vim's keybindings.

You seem to misunderstand: The government's position is not at question here. Their use of influence to suppress free speech is.

This article is about highly credentialed and respected scientific exists who were being deplatformed: not whackos. How can you judge anyone as "whacko" when you're prevented from even hearing opposing data? That's not how science works.

Okta just asked me to add a third authentication factor to my account. Now in addition to entering a password and authenticating via push notification I am also required to enter a code sent via SMS to the same phone that just answered a push notification. Sheer madness.

> When you say European, except for the fact that Tolkien wrote the story, what part of the show thus far has given you an explicit European feel?

"Middle Earth" was an old phrase used to refer to Western Europe in several Scandinavian languages. Tolkien, being a linguist, would have known this and chosen that turn of phrase deliberately.

Went through a series of interviews back in March - May. Got several rejections recently, 4 - 5 months after my last communication from these companies.

Yeah, it's okay. I got the message already.

Many micronutrient USRDA recommendations are mere guesses. Evidence is mounting that consuming the recommended 1g of calcium daily may actually be harmful for your health. Saturated fat - once painted as the enemy by doctors and nutritionists - has since been found to be negatively correlated with heart disease. I think before we get anywhere near trying to regulate or even recommend what people eat we first need to do a lot more study.

Just wait until they figure out that Apple's LIDAR causes cancer if you scan yourself with it 15 times a day.

For a while I had a phone with a broken camera. Got a new job. Company requires scanning a QR code to authenticate. "I can't - my phone's camera is broken." IT has no idea what to do. After two days of being locked out of services needed to do my job they finally manage to add an exemption for 24 hours to my account. The exemption somehow stands to this day.

No, they did not provide a work phone.

This is 100% at odds with both GDPR and CCPA. Should be interesting to see how the laws battle it out.

You're the reason spam works.

Is a CEO publicly accusing someone publicly of "ineffective leadership and poor performance" a libelous statement?

Sounds like Fedora is sacrificing good code for ideological purity.

Paypal has a "reverse charge" button. You should be able to cancel any payment within a reasonable timeframe.

(Meanwhile, Google flags every log-in from my daily Linux driver as a potential security issue. Madness.)

Likewise I have no fewer than three people trying to use a gmail address I've had since 2003 as their own. It's extremely frustrating - one even sent me $45,000 in a mistaken paypal transfer and then when I reversed the charges I was hit with an overdraft since I had made a Paypal purchase (which would ordinarily come from my direct bank funds) not knowing the money had been sent to me in error.

It shouldn't be this easy to use someone else's email address.

Yes but the premise is about tooling changing. Most commercial backend tools in Python are still using Django or Flask. That doesn't mean no new libraries will ever emerge. It's just that the pace of change is slower.

I'd say most of those are infrastructure rather than back end

I got a Dell XPS 13 in 2013 and loved it so much I decided to only buy Dell laptops from then on. It lasted four years and I only upgraded because I wanted something with better specs. I'm not sure how many computers I've had since then but I typically have 3 - 4 at any given time for various purposes. I got a pair of nice HP machines around 2015 and tried a couple Chromebooks but have otherwise stuck with Dell. Then in 2021 around June I decided to go high-end for my daily driver. Got a $2100 laptop from Dell and was very pleased with it until December. It was on my bed reading and had the computer playing some music on YouTube. I glanced over at the screen and saw it flicker. Concerned, I reached for the computer and before I touched it the screen went black. The computer never started again. I bought the same model with slightly more SSD space to replace it. That one died the same way after less than 48 hours. Because I install Linux on my computers I expect the warranty was voided so all I could do was swear off of ever purchasing a Dell again. Currently satisfied with a much cheaper HP. It's not ideal but I can get my work done.

Try https://booky.io

I think about this constantly while reading Hacker News. So many articles and comments by people whose level of enthusiasm doesn't match their experience. Try to voice a comment that goes against the flow of that enthusiasm and you'll be downvoted to oblivion, even if you speak with more experience and context than the masses. I'm horrified by some of the stuff I see here and feel like it's often useless to speak out.

> So far, I got rejected from over twenty job opportunities.

That's nothing. I've been continuously employed for over 20 years. I just got a job a few weeks ago after two months of unemployment. I kept a record of every application and in the end there were more than 130 of them. I ended up with several offers and got a great job but I had far more than 20 rejections for every offer I received and I consider that a very good result for the outcome I had and wouldn't refer to it as "a slap in the face".