Ya, this is the core of the disagreement that I would run into with the old school lispers.
I see it, I do, my third eye is open. I get the entire flow that the interactive development environment brings to the table and how it is infinitely superior than what existed in every other language for decades.
But I don't like it more than the modern tooling. That's pure personal preference. I don't like this weird stateful thing hanging out in the background of my dev environment. I don't find value in sending random expressions into the weird stateful blob. If I wanted to drop into a debugger, I'll ask, don't hijack my stacktraces.
I write tight test loops, modify my code, run the tests from scratch in the same one-key press the lispers use to evaluate their s-expressions. I don't need to go back and verify my build or application works from scratch, it never breaks, I'm constantly rebuilding.
I would run into situations not infrequently where some post-doc wasn't quite sure how they achieved the state they did in the image, had a bug, but no tests to reproduce the bug or anything else. Maddening. An anti-pattern I never saw accomplished to the same degree with the Python boys (not to say Jupyter Notebooks aren't their own stateful fucking mad house of bad software engineering).