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ogwh

230 karma · joined January 2, 2018

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ogwh··on So I finally sorted out what happened to my brain
No. Adderall forces the brain to release the dopamine it already has and causes increased brain activity, using more glucose. It's more likely to cause this condition or make it substantially worse than it is to treat it.

The amphetamine molecule enters the neutron and does several things, two of which are:

1) Force dopamine that is in storage in the neuron to be released prematurely.

2) Reverse the direction of the dopamine transporter so that free dopamine within the neuron that hasn't been reclaimed yet is forced back out into the synaptic space. Usually the transporter moves dopamine from the synaptic space back into the neuron.

To restore dopamine levels you'd need plenty of rest and a healthy diet. Forcing the brain to use the last dregs of dopamine it has left with drugs would be the worst thing you could possibly do.

Edit: In short amphetamine doesn't replace or substitute for dopamine, it just forces the brain to use what it already has. If you're running low it's going to mess you up.

ogwh··on 'Ice-cream toothache': Cold food and drinks pain explained
Eugenol is a local anaesthetic AND a severe irritant. When you apply it to a tooth and it comes in contact with the gum both end up numb. Until it wears off and you have what amounts to chemical burns on your gums. Using eugenol to treat tooth sensitivity isn't worth it.

Do NOT try using eugenol for tooth sensitivity.

ogwh··on Is Anyone Else Just Done?
I left technology behind almost completely a year or two ago. What I've realised is that most technology doesn't improve our lives, it complicates it and makes it measurably worse. I still check HN, which is probably the last remaining symptom of my link to the tech world.

The world needs less software and less technology, not more. The further down this rabbit hole we go the worse everything gets. Physical health, mental health, social health and the broader links that bind society together all suffer.

It's all noise and its supposed benefits are, for the most part, an illusion.

There's definitely a role for tech to play in our lives, but a limited, balanced role. We're living in a world saturated with it, overdosing daily.

Give it all up, move on, and in time you will recover. Even if it takes years.

Good luck.

(It's unlikely that I will return to read any replies to this comment.)

ogwh··on No-deal Brexit opponents defeat government
Exactly, they can't. That's been Boris' point all along, and why he's calling for a general election tomorrow as a result of this. But rumour has it that the opposition will vote against a GE too, forcing Boris to negotiate in this circumstance. It's absolutely appalling.
ogwh··on Acute Effects of Electronic Cigarette Aerosol Inhalation on Vascular Function
I started with a myBlu and ended up going through 6 different devices before finding one that doesn't suck. There is a huge quality problem in the market at the moment. The device I settled on, and which I've had zero problems with, is the "Smok Nord AIO 19". It's about 25GBP. Note that I had also bought a "Smok Novo" and DID have problems with that, it leaked everywhere, so even within the same brand quality varies dramatically.

The reviews on YouTube aren't useful because they don't usually use a device long enough for problems to become apparent. I've been using the Nord AIO 19 for several weeks now and swear by it. And it's not to be confused with the regular Nord... Which looks like the Novo and also has leaking problems.

If you're in the UK, Totally Wicked are a company that, while expensive, can be trusted. They only sell quality devices, but they're all rebranded versions of other manufacturers. They've recently struck a deal with WHSmith who will also be selling their kits (that's how trustworthy they are).

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