rdmcfee

I can second that. Ketosis and fat adaption reduces the need for constant refueling. I have no problem going 24 hours between meals and exercising while fasting.

I typically eat ~12 meals per week, 2000 kcal per meal.

In addition, the consistent mental acuity achieved in ketosis is fantastic.

In Canada the second largest group by religion is "no religious affiliation" http://globalnews.ca/news/544591/the-second-largest-religiou...

In BC over 35% are non-religious. In Vancouver it's over 41% with only 5,000 more Christians than "non-religious". http://www12.statcan.gc.ca/nhs-enm/2011/dp-pd/prof/details/p...

Poor date/time libraries are a major source of long term pain for developers. Hopefully Rust will get this right early on!

This is terrible reporting. I couldn't find a single specific study referenced in this article. Another example of the media obfuscating science. Only opinion articles by epidemiologists who seem to have a hankering for pursing non-causal science.

This could just be a correlation but the BTC/USD price seems to be inversely correlated with MtGox news. Trending down when rehabilitation/takeover looks promising, trending up when Willy report comes out and the momentum of the takeover bids seems to stall.

I tend to agree with you. Earth has always been in a constant state of change.

We seem to have this perception that Earth's current state is optimal and that any change is bad. Certainly change could bring adverse effects but the premise that we're "ruining the planet" is too easily accepted. If we were living during the last ice age and having this discussion, our descendants in the common era would be having a laugh.

I love the contrast between Earth and Venus.

Earth: devastated by drastically rising carbon dioxide levels (from 0.035% to 0.07%).

Venus: 96.5% atmospheric carbon dioxide. No problem! Terra-forming!

People fear change. This revolution will require adaption and there will be pain involved, but mass automation will create vast wealth.

Prehistorically we spent our entire lives simply collecting enough food to survive. Since then we've gradually been able to devote a smaller and smaller portion of our lives to fulfilling the requirements of survival. Mass automation will continue to reduce this. There will be growing pains but the trend certainly continues in the right direction.

In this case "worst" depends on whether you're a developer or an employer.

I think the idea of observational epidemiology is 2 fold. In extremely rare and specific cases (like with smoking and small cell lung cancer) cohort studies show such extreme correlation with new or rare diseases that causation can be implied. This is most certainly not the case with this study.

In other cases observational studies are used to look for a strong correlation which can be used to justify a much more expensive interventional study which could actually be meaningful.

From my account of the paper it's not apparent that the correlation is even strong enough to justify proper research. Something along the lines of proving the correlation between eating ice cream and drowning.

Just wanting to reiterate that this is an observational cohort study that shows only a weak correlation. There's no casual information at all in the study referenced in this post and the correlation is so weak that it's unlikely to even provide useful hypotheses for future interventional studies.

Everyone I know who's a vegetarian was a bit wacky to start with :)

Soylent could be considered exactly as acceptable as any specific food but most other diets offer a very wide diversity of foods. The current thinking in nutrition science seems to be that diversity in diet gives us a better chance of eating how we should be eating. Because we don't actually know how we should be eating we rely on that diversity. It's naive to think that the definition of "nutritionally complete" (which Soylent adheres to) isn't going to change over the coming decades. A traditional diet will still have a chance of being "nutritionally complete" under future requirements whereas Soylent's exact formula almost ensures that it won't.

I think what's even more important are some of more complex functions of digestion and nutrition response. For example, what is the glycemic response of Soylent? In December Annals of Internal Medicine published a study (1) showing that a daily multivitamin has no benefit to the longevity and health of the average American but we do know that dietary interventions which increase dietary intake of certain vitamins via actual foods are beneficial to health. Scientists are still figuring out why but it is apparent that you can't just take a pill or formula containing certain nutrients and gain the same benefits of getting these nutrients through food.

(1) http://annals.org/article.aspx?articleid=1789253

This was touched on in the article but I still feel it's necessary to point out that nutrition is one of the least understood fields in science.

The primary reason is that there are almost zero proper clinical trials and interventional studies. We have thousands of cohort studies which prove almost nothing.

For example, for 60 years saturated fat has been considered the enemy of cardiovascular health (because of some poorly conducted cohort studies in the 60's and 70's). Just this March, BMJ published a major meta study that showing that there are no proven causal links between saturated fat and heart disease. In fact it is now being suggested that avoiding saturated fat has been detrimental because Americans have replaced fat intake with high glycemic index foods causing obesity and T2D.

Personally I have no doubt that Soylent will fail to provide some required nutrient or fail to induce a certain hormonal or chemical response which is obtained via natural food intake. We simply don't understand nutrition well enough to check all the boxes. That said, if Soylent wanted to follow the scientific method and conduct a proper interventional clinical trial with a control group, adequate study population and duration I would be happy to consider the results.

Coming from the healthcare marketing field, I can tell you there are many doctors who are looking for more patients. Especially specialists.

Tuition at UBC med is $16,000 per year and many students qualify for up to $100,000 in bursaries. After 4 years of academics there is a paid residency. It's not a huge salary (~$50k) but enough to avoid going into debt.

In my province of BC, all payments from the Medical Service Plan (MSP is our public insurance system which costs Canadians a maximum of $65/mo or as little as $0 for low income individuals) publishes all annual payments to physicians:

http://www.health.gov.bc.ca/msp/legislation/pdf/bluebook2012...

The average for Family Doctors is around $240,000 CAD and for specialists is about $430,000.

Average registered nurse salary in BC is about $61,000 CAD.

In Canada our GPs are paid approximately $31 for a regular visit. They pay their overhead out of this $31 and still typically keep 65-70% of their billings.

It's amazing that the billing costs in the US are a factor of magnitude higher.

There's no evidence that the profession causes doctors to commit suicide. It's not a stretch to hypothesize that people accepted to medical schools are self selecting for perfectionism and bipolar disorders.

Many people experience some ketone body production and metabolism well eating SAD (standard American diet). Fasting overnight and skipping breakfast, or having a long workout more than 4-5 hours after your last meal will cause this.

Nutritional ketosis, unlike ketoacidosis is a loosely defined term. Everyone has experienced it on some level. Perhaps just not at extreme levels like people pursing NK with vigour.

On one hand this makes sense. The IRS is trying to avoid early adopters from cashing out millions by purchasing goods to avoid paying capital gains tax.

On the other hand, this is debilitating for people who want to use BTC for day to day transactions. Imagine the paperwork involved. <- opportunity for a wallet app which tracks gains/losses

One thing is clear. There's a lot of information yet to come. They've indicated that it's "highly probably" the coins were lots due to the TX Mal bug which seems to be the least likely hypothesis in the eyes of the community.

I suspect they're still analyzing their logs to find the full story themselves.

I would think that insider theft is one of the least damaging outcomes for the Gox depositors.

Unfortunately I don't know that the Japanese government is going to have the technical expertise to properly identify the theft and track where the coins have moved. I can't imagine that the thieves have managed to squander all of the 750k BTC.

I believe it was included as debt at the artificially low GOX price.

Their cashflow hasn't halted. There are still plenty of trades happening between current GOX customers and they still get trading fees on these trades. The problem is that their customer acquisition and retention will take a massive hit because customers can't withdraw their coins (or fiat in a timely fasion).

The market is clearly betting against MtGox having a fix soon. Based on this article it seems like their revenues are strong but their customer acquisition and retention will suffer immensely if they don't manage to re-instate withdrawals.

I find it hard to imagine that they won't solve the withdrawal concern soon. Especially with today's update.

Modification of promotion and pricing seem to make sense to me.

Education is important but for many people in the developed world their exposure to liquor ads on TV is a lot more prevalent than their exposure to education. You're fighting a losing battle if you're competing directly with the messages of liquor companies (same thing in tobacco industry).

As for pricing, in many countries including the US with their new insurance system the cost of healthcare is being shared across large groups. In Canada we tax liquor at a rate of about 130% and feed much of that revenue directly into our healthcare system. This way the more you drink the more you contribute to your future expense to the healthcare system.

> Only human beings have science labs and clinical research studies to come up with new defenses against the thoughtless, largely immobile threats from other living things

We're giving bacteria (which reproduce rapidly and mutate quickly) the perfect natural science lab to mutate and select for antibiotic resistance. There are 10^14 bacterial cells in the human body vs only 10^13 human cells [1]. Their reproductive cycle is over one million times faster than ours.

We're creating the perfect conditions for rapid evolution of these organisms. This system is executed by billions of billions of bacteria continuously and we're trying to combat that evolution with a few thousand humans in labs.

It seems to me that the take-away here is we need better engineering of our own solutions and we need to find a way stop enabling this rapid evolution of bacteria.

[1] http://dx.doi.org/10.1146%2Fannurev.mi.31.100177.000543

I wonder why the coinbase prices are inflated to almost the GOX price. Are there market makers and scalp traders driving up the coinbase prices now? From my experience coinbase doesn't have the withdrawal issues like gox

Any guess on correlation between location of applicant and proximity of application time to deadline? Is the 8pm PST deadline keeping the European applicants up late?

In the context of the article your first point is the key question. The author argues that the flow rate is relatively constant even with varying speed. I would tend to agree that it would be fairly constant but if there was extremely efficient merging I could see the flow rate increasing by a few percent. Theoretically the difference in flow rate if cars maintain a 2 second delay from the previous car should be the difference in the length of time that it takes the actual length of the car to pass through the merge point.

So if the car is travelling at .5 carlengths per second then the duration per car should be 4 seconds whereas if the car was travelling at 10 carlengths per second the duration per car should be only 2.1 seconds.