2,190 karma · joined August 9, 2010
Does the upcoming XLA interact with this as well? I.e. compilation would be too costly for dynamic graphs, and so it would only make sense for static graphs?
There’s a certain way to doing this which I believe is key to success. It can’t be about doing molecular dynamics from atoms on up, because of computational considerations, and because that’s useless anyway (one wouldn’t learn anything beyond the known physics and maybe better force fields and sampling techniques). It also can’t be like the kludgy attempts that have been made so far (e.g. Markus Covert’s paper in Cell from a few years back—it’s perfectly alright work, but won’t get us closer to solving this particular problem.) Instead, I think the key is to develop a new layer of abstraction for describing biological phenomena, much like say organic chemistry is a genuinely new abstraction built on top of physical chemistry (which is itself built on top of QM), that hides away the irrelevant details (e.g. most of QM) while capturing what’s salient about the biological phenomena of interest. It would require advances in the aforementioned areas of models, theory, and tools, that are made in concert with the aim of simulating a cell.
https://blog.twitter.com/2015/autograd-for-torch
EDIT: To be a bit more specific, autograd just requires that one writes the forward model, and it can involve any program logic like conditionals, etc, so long as the end result is differentiable. It then takes care of all the gradient calculations.
1. Will the model be group-based where there's a head PI setting the research agenda for a group and researchers working under the PI? If so, what level of independence do you expect individual researchers within a group to have? I.e. is it more like the academic model with postdocs enjoying a fair degree of independence, or more akin to national labs where the research agenda is reasonably fixed and everyone is expected to contribute to the same research program? Or, are you coming up with an entirely different model?
2. In general how hands-on will YCR be in terms of intra-group management?
3. Do you expect to subscribe to all the major publishing houses so that YCR researchers have access to journals like they would at a top-tier university?
http://news.sciencemag.org/plants-animals/2015/04/judge-s-ru...