untilHellbanned

Ok so my 20 years in the field means nothing to trolls. I can live with that.

Ok so me-too apps like yet another photo sharing app is not cool, but me-too incremental biomedical research is cool.

Good to know we are all about innovation here.

no. more practical to use proxies (this is the hard part) from more readily available tissues like the blood.

I'd bet any amount of money that this data already exists in some form and so re-inventing the wheel - haha - with this study was not particularly useful. Like the parent comment says, water is wet. When you exercise stuff changes. What most biologists never do is point out all the things that don't change. That's how we'd see how special it is in this case that telomeres change.

I didn't say anything about risk. My comment was exclusively about effort level.

There is no part time as a med student. I was md/phd and dropped the md because no time to do both reasonably well. You can eventually be a part time doctor but have to pay many years of dues giving 100% effort. It's not dissimilar from being a startup founder.

Molecular biology professor at an elite school here with over a decade of experience in what's regarded as one of the most critical aging pathways. Nothing to see here.

Cool but it's a non-starter if you go beyond a few thousand rows.

Complete beginners don't need flexbox.

Ye ole anecdote to the rescue. Ignoring the point of the article.

Oh the irony of poorly articulating one's smartness. This is smart in the "excellent sheep" Deresiewiczian sense (1). That's what goog/face/harvard is a safe harbor for. Oh and smart people don't sit around thinking about who's smart. That's just some garden variety vestigial junior Olympiad wannabe BS in action.

https://mobile.nytimes.com/2014/08/24/books/review/excellent...

Alot of people want a wikipedia/github-like system but nobody will go there until it has the prestige. Academics are not early adopters. They are followers. I'm a professor in a STEM field at a major university so I'm speaking from experience.

Having the luxury of time and money like the OP has allows for an extensive checklist like this. Kudos for putting it out there and for fighting a good fight. However, many people don't have the bandwidth or financial stability to divert activity away from non-stability generating activities.

Sadly the more I thought about this, the more I'm finding it difficult to see any internet posts as anything other than contributing to a constant stream of agenda pushing and/or humble bragging. FB started it and I fear now we a stuck with everything (including of course these comments) washing away in a sea of noise.

Though none of those things are life and death so not sure relevant.

> We're all too busy focusing on our own shit and own insecurities to worry about anything you have going on in your head.

YES.

Also physical performance for most sports is objective and earned, whereas most other scenarios it was a subjective process decided by other humans.

100% on point. That's why I'm insanely happy to live in St. Louis now right as our kids were born one mile from grandparents. We avoid most of that stress. As long as you work at a thriving place it feels virtually no different intellectually than SF. After all think about how many people you interact with meaningfully day to day. Seems like most people's work are little bubbles so the city you live in isn't super relevant.

So that's the problem, "we" virtually never recognize that the builder is the right one for the job. The charismatic person always gets the job/money/fame/whatever.

So if the journals must be made available instantly isn't the business model gone? Why would anyone have to subscribe anymore?

Yes this specifically excludes Nature, Science, and Cell, which is critical because those are the career-making journals all of us academics must currently bow down to. Please Gates Foundation force their hand!

A refreshing, balanced post-mortem. Keep trying guys, you'll hit upon something.

i mean do employees really want to deal with work stuff via text message too? We have email, calendars, various video and chat messaging apps, old fashion face-to-face communication, etc.

I'm pretty sure employees want to feel less on call, not to mention keep their one last silo of personal communication free from yet another greedy overlord.

so btw you don't want to inhibit GSK3. Likely an academic only finding.

Yes all valid concerns. You and I will get downvoted for even mentioning these companies in a pessimistic light but it doesn't make it less true.

That he contributed to.

We had the same thought over a year ago. We choose Bootstrap 4 but it was a big headache because the Javascript plugins were and still are quite busted. I would choose BS3.

Why did YCombinator blog switch to Wordpress from their own "free forever" Posthaven solution?

Their new site feels tacky and generic kinda like this blog post. Taken together with less news on larger batches of startups in recent years, it feels symptomatic of a slow dilution/degration of the YC brand.

Seems odd so this means the money making isn't going that well.

Nytimes has jumped the shark. I'm dead serious in saying its days are numbered.

It's totally on topic. The media is telling us to quit social media. Whereas I'm saying we should quit the media. It is also most definitely something new as most people aren't pointing the finger at the New York Times. Both these points should be quite obvious but they weren't as I suspected which is ironic because it led to canned, low value rebuttals.