You are insane. Are you even being honest with yourself here? Why would you put up with less pay and higher cost of living? What better lifestyle is there to speak of that bigger cities south of the border doesn't provide you? The mountains and ocean? They got that over there too.
The only reason I think you might be saying this is the same thing people without any other choices say, that it is the best choice. This is textbook cognitive dissonance.
edit: well looks like you are a recruiter which explains a lot why you might be pushing this crazy idea. I've ever heard of Zymeworks Inc. https://news.ycombinator.com/item?id=7337161.