Go to your local user group meetings. Java, Ruby, Php, Python, .Net, Flex, whatever. (If you get too niche chances are you'll strike out). Typically there are always someone there handing out business cards, or job postings. Take it and send them a nice email introducing yourself the next day along with your resume.
If you have friends that have been out of school for a while try and connect with them. They might know of good people to put you in contact with.
LinkedIn is like crack for recruiters. Make sure you're on there and have some of your experience on there. Connect with people. You'll start to see who is a recruiter very quickly (500+ connections) chances are they're a recruiter. LinkedIn helps you keep in contact with recruiters if they move companies too.
Put your resume on Dice. It can take a month before that pays off because it takes a while for your resume to make the rounds.
The economy sucks, but IT is bouncing back quicker than other sectors.