Honestly, there are plenty of other options out there besides Angular and even React, despite the tremendous hype around it at the moment.

Aurelia seems to be the best ideas from Angular + the best ideas from the creator's previous framework, Durandal, in one framework with much cleaner syntax and much less complexity than both Angular & Angular 2.0.

Ember has made some big updates recently, rewriting their rendering engine to use a virtual DOM.

A lot of people still seem to really like Meteor.

Mercury, Mithril, Ractive, JSBlocks, etc. are all smaller, lesser known projects with a lot of potential.