My sense, playing with Perl 6, is that it could become a "pro tool" -- very deep and powerful. It needs to mature some (though it is very solid already) and to grow its ecosystem (though it can run much of CPAN via Inline::Perl5).

Those who want to play can install from http://rakudo.org/how-to-get-rakudo/

Larry's talk was a lot of fun, especially the way he zipped around between vi and terminal windows -- no need for presentation software.