It's never worth it. For $6k you can get actual protection for some time before you upgrade your infrastructure.
There are two kinds of protection, basic HTTP/HTTPS and DNS only (done with DNS and CDN like servers co-located at peering points), and traffic filtering that is done through BGP with and a GRE tunnel. While you can get basic HTTP/HTTPS and DNS from CloudFlare for $200/month on a business account, what ProtonMail needed was a BGP/GRE which at it's lowest price is a multiple and an order of magnitude more expensive.