On this topic silphium went extinct despite being highly useful medically [1].
From your own source, "The identity of silphium is highly debated."
-_-
That makes me wonder percentage of the world's farming is done under a patent.
In regards rhinos I was responding to the claim that if the rhino horn had real medicinal value it would be farmed. It could be possible (very unlikely) that rhino horn does have real medicinal value, but there is no way of ever showing this without a patent on rhino horn. Without a patent you can't farm rhinos for medicinal purposes because you can't ever show rhino horn has medicinal value (i.e. No pharma company will invest the money required to show this without a patent).
You can't use the fact that rhinos are not farmed to prove that rhino horn has no medicinal value when there are other possible reasons that rhinos are not farmed for medicinal purposes.