Personally I really enjoyed this talk. As a business school grad who taught himself to programme and now works for a bootstrapped web startup, I still value what I learned at business school. I think DHH is a bit harsh with the 'unlearn' label. I consider the core principles learned at b-school to be very important to shaping my everyday thinking. It is the specifics (DHH's example of Porter's five forces applies here) that can be forgotten. But those specifics were a great tool for developing the overall business mindset that he also describes. I don't regret my time there whatsoever.