POSIX?
Its quite possible to have a C-based sockets-/signals- handler in a single source file, say .. 48k lines of code or so. I've seen many robust system daemons with just such an implementation.
3rd party dependencies are definitely an issue that very few languages have managed to promote, since languages either want to promote (or demote) such circumstances as mass-package (i.e. mass usage of the language) in a broad commercial/industrial/social context.
But its not naive to write such things as a Wiki and a Blog in C. Just .. dangerous. I imagine there are, however, some good 3rd-party C libraries available to do less-dangerous implementations, however...