He hasn't found that he experienced leg pain or much fatigue. He takes routine breaks, preferring to jog in place to refresh his legs, rather than sitting down so much (he noted he takes breaks for eg lunch, I assume he sits down for that). He said he basically hasn't experienced any significant negatives.
On the positive, he said his legs and back feel much stronger. He had back pain for years that is now gone. Early on he wore specific sneakers and was very careful about doing things a certain way; now he has relaxed that a lot, and will wear any type of shoes he wants to, and doesn't worry about having a padded mat under him. He didn't indicate a vast uptick in productivity, but that he may have experienced a bit of improvement there. He said his posture improved dramatically, having removed the hunching-over you often get at a desk.
His posture has improved and doesn't fatigue as easily when standing but don't expect it to drastically improve your life, because overall healthiness is an accumulation of many things.