I have a doctor who has prescribed me Xanax strictly for flying, in which case I take a lot and it sort of just knocks me out. The problem however is that roughly three weeks out, if I know I have a flight, I will start to really stress, obsess about the upcoming flight, have difficulty sleeping, etc... And like most of us here on HN, I consider myself a logical person who understands the safety of flying, the statistics and the likelihood of events, yadda yadda, but it doesn't change the fact that for me, I feel extremely uncomfortable flying. I don't know whether it's the lack of control or the anonymity of whoever is in the cockpit, but sitting on a commercial jet coincides with me feeling panic.