https://www.youtube.com/watch?v=vS47RVrfBvE main system board
https://www.youtube.com/watch?v=_poMPOUGRa0 memory risers
Edit: Supermicro has several 2TB boards, and even some 3TB ones: http://www.supermicro.com/products/motherboard/Xeon1333/#201...
(Disclaimer: AWS employee, no relation to EC2)
6TB is about where single machines currently top out due to the hardware constraints of multiple vendors and architecture, and memory bandwidth starts being an issue. You have to throw 96x64GB at the ones that exist so wave buh bye to a cool half a million USD or so. If you're sitting on a 12TB box I want a SKU (I want one!).
I don't actually think Supermicro makes a 6TB SKU, even. That's Dell and HP land.
Sure, http://www.supermicro.com/products/motherboard/Xeon/C600/X10... supports 3TB in a 48 x 64GB DIMM configuration.
This shows a logical diagram of how they cobble all these cores together: http://www.redbooks.ibm.com/abstracts/tips0972.html?Open
I've seen these both opened up and racked up. They are basically split into max 4 rackmount systems, each I think was 2U IIRC. The 4 systems (max configuration) are connected together by a big fat cable, which is the interconnect between nodes in the Redbook I've linked above. The RAM was split 4 ways among the nodes, and NUMA really matters in these systems, since memory local to your nodes is much faster to access than memory across the interconnect.
This is what I observed about 5-6 years ago. I'm sure things have miniaturized further since then...
4 CPU, 60 cores, 120 threads (cloud cores), 3TB RAM, 90TB SSD, 4 x 40GB Ethernet, 4 RU. $120K.
Same price as the AWS instance for one year of on demand.
One of the links on the top points to a server with 96 DIMM slots, supporting up to 6 TB of memory in total.