Yup. When I lived in Venice I went to great efforts not to cross the 405 for errands unless absolutely necessary (and even then, tried to batch trips if possible). If Expo II had been around I might've taken that across the 405 instead of driving.

By the same token, if you move to the Westside from pretty much anywhere else in LA, you'll get tons of shit from your friends who now have to go over the river and through the woods to see you.