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Given the size of those 2 monitors it doesn't really look like a smallee form factor would have been an issue?

As its a standing desk I have, having everything on the desk makes life easier.

Mini ITX would have taken up alot of deskroom. My old case (Antec P183) I had sitting on a side desk before hand

I'm thinking about doing a similar setup and I like the smaller form factor because I can attach it to the back of a monitor and not even have to look at it.

Take a look at the Antec ISK-110. Not as small as the NUCs, but lets you build your own machine on the cheap, and still designed to be attached to the back of a monitor.

(Won't fit a standalone GPU, but I don't think anything that can be attached to a monitor can)

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