Lua has the same property that global methods are hash table lookups. What LuaJIT does is that it specializes hash table lookups to the key so that looking up an item in a hash table is two instructions which can be executed at the same time on a super-scalar CPU.
LuaJIT also gets serious wins from lifting the lookups out of loops since they can't change. This is only due to the fact that Lua doesn't have threads that can muck with each other's state. JRuby+Truffle solves this with multithreading by assuming that it doesn't change and deoptimizing into a slow path if it detects a change.