In response to @pcwalton:
> In the case of an I/O bound Web server, I don't think that Go is going to appreciably result in "leaving money on the table". Python releases the GIL on I/O, which is where your time is largely spent.
GIL doesn't matter, the OP said he was writing single threaded application. This means he's doing async (unlikely) or blocking the entire application process (not just the current request) on I/O.
> Linux is very fast at spawning threads. When you're doing I/O, it doesn't matter.
Not as fast as goroutines, and spawn speed isn't the only (or even the most interesting) measure of efficiency--you can run several orders of magnitude more goroutines on a Linux box than you can threads. Of course, none of this is relevant to this conversation, since the OP is talking about running a single-threaded Python process per core.
> Go's concurrency is not "fundamentally different" from any of the other languages. It's just an implementation of thread-per-connection in userspace. This is an implementation detail, and for a typical Web server I think it doesn't matter much.
You're conflating Go's concurrency model with its webserver implementation. Go's concurrency model (movable M:N coroutines with implicit yielding and a synchronous abstraction over async IO) is fundamentally different than the other approaches (threads and vanilla coroutines with some blend of sync and unabstracted async I/O).
Since you mentioned thread-per-connection, Go's "threads" are much lighter than even Linux threads, so you can service many more simultaneous connections (by many orders of magnitude in extreme cases). This is especially true if you're not using async I/O, and blocking I/O is the default for most of these other languages.