There will probably never be desalination cheap enough for irrigation, and non-agricultural uses don't add up to enough to make desalination nescessary.
The key form CA is not to replace all water sources, but rather close the gap between rainfall and water needs. Right now, we are doing this by pumping ancient water from aquifers, but as solar power and desalination techs mature, the price will come down and will likely be sufficient to cover that gap. The recycled water will also factor in.
http://israelnewtech.com/2016/07/california-shifts-gears-wat...
http://www.jpost.com/Business-and-Innovation/Environment/Isr...