The current pipeline for such a request would be the GPU sending a request for more data, the CPU receiving it, the kernel figuring out who should handle the request, the handler then making a request to the kernel for the data on the SSDs, the SSDs sending the data back to main memory, the kernel telling the handler where the memory is, then the handler telling the kernel to send the memory to the video card.
In contrast, the route with the on-board SSDs is that the GPU makes the request, the ASIC that handles NVMe requesting from the memory chips, the memory chips sending to the ASIC, which goes into memory. There are a lot fewer steps there, and a lot fewer places where delayed interrupts, etc can introduce lag.