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Would be nice if someone could update the previous NixOS vs GuixSD discussion: https://news.ycombinator.com/item?id=8246338

Which is also worth mentioning, builds part of its package management on top of nix https://www.gnu.org/software/guix/about/

In a similar vein is Intel's Clear Linux[0]

https://clearlinux.org/

Clear Linux is much more focused on the "containers as VMs" direction than nix or guix are (Use the $PATH instead of containers, no virtualization of network cards etc).