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Comment by harperlee | Hacker News Reader

So could we engineer ourselves to be able to withstand more radiation? Perhaps with advances in cancer treatment and CRISPR-style modifications on the most fragile parts of the genome we can make us more resilient so we can become a multiplanetary species...

On the other hand, sending life to Mars, due to that radiation, would make it evolve much faster, right? Perhaps we can start terraforming it and study the evolutions of plants and animals there to gain insight in how to overcome our frailties.

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I just read they sequenced the Tardigrade DNA and have found a protein that protects against X-ray related DNA damage.

> Using human cultured cells, we demonstrate that a tardigrade-unique DNA-associating protein suppresses X-ray-induced DNA damage by ~40% and improves radiotolerance. These findings indicate the relevance of tardigrade-unique proteins to tolerability and tardigrades could be a bountiful source of new protection genes and mechanisms.

http://www.nature.com/ncomms/2016/160920/ncomms12808/full/nc...

I'm not sure of the exact amount, but water can be used for shielding.

So maybe we end up with huge domes made of tanks with 20' of water in them.

Also, since Mars has CO2, I'm guessing once a dome is up, we simply pressurize it with the surrounding atmosphere? Once pressurized we could use O2 tanks and cannulas, or add plants?

I fear that there is going to be a huge political debate first -- a lot of folks are going to say that man isn't worthy/able/competent/etc to colonize another planet.

> On the other hand, sending life to Mars, due to that radiation, would make it evolve much faster, right?

The bottleneck in evolution isn't mutations but selection events (~= number of organisms).

Oh, I didn't know that. But wouldn't a larger mutation probability result in more variability and hence quicker findings of improvement paths? (plus avoiding local maxima)

Sure more variability means stronger selection, but bigger mutations are less likely to be positive mutations so more selection events need to be spend to get them out of the gene pool again.

Not anymore, at least with CRISPR.

You would have to modify the psyche extremly to adapt it ti the social circumstances of space

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