This is good news. I like how they identified a precise mechanism that might contribute to it. Maybe eliminating at least one of these three in the body might knock out or reduce the condition. Depends on if other stuff is involved.
For artificial joints like a hip and a knee joint, you have a lot of exposed materials like titanium, stainless steel, or medical polymer, so it doesn't have an immune system. Getting a biofilm infection forming on an artificial joint sometimes means taking the implant out, even if it's working fine.
So biofilms are a tough problem. They're far more sinister than conventional bacterial colonies. Since this is in the digestive tract, I wonder if some type of detergent can be found that simply dissolves the film matrix, washing away the bacteria and fungi.
And, I guess the biofilm in this case is especially tough. From the abstract:
The mass and thickness of triple-species (C. tropicalis plus S. marcescens plus E. coli) biofilm were significantly greater than those of single- and double-species biofilms.
On the other hand, something like Crohn's means your microbiome is already damaged, or at least not optimized to make a positive contribution to your health. Fecal transplants from healthy donors have shown promise in similar circumstances; if you're interested in treatments for such conditions, that might be a good place to look.