How does this now-patented "ISRIB" molecule compare to Leonard Guarente's research[1][2] on nicotinamide riboside and pterostilbene supplementation?

[1]: http://nymag.com/scienceofus/2016/08/is-elysium-healths-basi...

[2]: https://news.ycombinator.com/item?id=12345526