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I would say mithril.js for the frontend and Flask for the backend is pretty good, but that's just my favorites. There are plenty of other good ones, and neither of those are particularly popular.

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Personally, it's more important for me to have fun while coding than using "popular" tools. In the end, your end users don't care as long as it works.

I use flask for a personal project of mine, but instead of Mithril for the frontend, I use http://riotjs.com/. I find it much more readable for someone who has been working with HTML/CSS for quite some time.

Yeah, it amounts to what you like.

Do you like HTML-like templating and a lot of sugar? Riot is the way to go. Do you like minimal magic, JS-style templates, and/or Lisp? Mithril is the frontend for you.

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