> In addition to standard package management features, Guix supports ... unprivileged package management, per-user profiles, ...

That sounds really cool. I wish I could install DEB packages just for my local user, without needing root access. I wanted this back at my university's computer lab, and I still want this on my own systems today.

These days a lot of people use personal single-user machines, so having it mandatory that packages be installed to the root file system is very restrictive. For example, I have a lot of DEB-packaged games from HumbleBundle, and it feels weird to need admin privileges to install them all across /usr/games, /usr/local/share and all that instead of just a place of my choosing under /home/me.