I challenge anyone making such claims to construct an even _moderately_ realistic example of where such reduction would be possible.
Here is a very simple and already very optimistic model that is still way below a 100x reduction: say my program consists nearly exclusively of sorting of various arrays and I write out bubble sort in full each time using for loops etc. rather than call a sort() procedure. Bubble sort takes roughly 20 lines of code to implement, so I would at best get a reduction of close to a 20x, rather than a 100x one.