Especially once you get into managing dependencies. Virtual environments (whatever this year's flavor is, venv I think?) are a mess. I was trying to get VS Code to execute a python project in its virtual environment but gave up and just went back to running it in a terminal. There's probably a way to do it, but I poked at it for a while and didn't figure it out.

Javascript might have its hassles, but even when you get to dealing with npm it's still more of a self contained thing.