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If (like me) you don't have a good working understanding of CRISPR, check out this fantastic episode of Radiolab: http://www.radiolab.org/story/antibodies-part-1-crispr/

There's also an updated version of the episode that they aired this year.

Just to add some info: The update recaps the original, and talks about advances over the year or two since the first one.

It's a great podcast episode.

And if you like the original episode, I also strongly suggest you listen to this: http://www.radiolab.org/story/shrink/

It is not CRISPR-related, but part of the same interview. It was really inspiring.