I don't disagree that there are risks.

But genetic reshuffling, recombination, and horizontal gene transfer has been going on en masse in the microbiota we are surround by for billions of years. I think once we start considering introducing truly novel genes, we will have a case for greater caution and reserve. But so far, all projects are of the 'transfer this already existent gene to this other organism', and I think that is a less risky proposition overall.