Nix doesn't integrate with Debian well - you can also use yum on Debian and nobody does that either. If you're using Debian, it's because you want to manage a Debian system with Debian packages.
I use Debian and I do not like to manage the Debian system with Debian packages. I use Debian because it is the community-backed distro.
A community-backed distro, surely? There's also Arch, and others.
Yeah, nix doesn't feel right on debian because it can't manage services and doesn't use the "standard" packaging idioms. Is there someone else with a different experience or a workaround?