I really dunno - I find React to work really, really well in the small and medium projects where I do (any) web work. Coming to React after years away from frontend development, and avoiding it because of things like jQuery, was really awesome because it demands that you enforce separations of concerns in a way that really appeals to me.

Hell, I generate HTML email with React, now. No reason not to; it's great. Simple, understandable tree of reusable components that have understandable data flows--sign me right up.

The biggest problem with it is the initial activation energy of a new project, which is partially solved through create-react-app and largely solved by doing it once in a replicable way. (I've been creating React projects off of the same base for quite awhile now.)