Async allows to maintain low latency permanent connections between each clients, being it a web page, a task queue, a server worker, etc. We finally can have it all connected. We can broadcast setting changes, propagate cache invalidation, push action notifications, update task completions to subscribers, allow everybody to react to stuff on the file system or the db instead of polling, all in soft real time.
The potential is amazing.
We all can do HTTP req / resp. The question now is: how good the tooling around this cycle is.
Have you looked at the options there / if there would be an easy way to bolt on a more async driven framework? Obviously, it doesn't solve the missing framework issue, but maybe there's some clever tricks you can do because uwsgi is allowing you to bend the rules.