"Shall I make a beautiful illustrative web-based experience or shall I make a site using Bootstrap?" said nobody ever.
As a designer these days I don't think there's anything like that kind of workflow available any more.
I actually made a similar argument yesterday to someone - whatever we feel about Flash as medium for normal web content or as a browser plugin, that shouldn't taint it's reputation as a content creation tool.
However I get the point, but I feel it is important to stress this difference that you bring up.
My 18 year old clueless self seen turtleshell.com randomly, thought it was amazing, looked up flash, did stuff in Flash, 10 years later OOP. 10 years after that, software engineering.
My 18 year old clueless self today would want to be like "somethingcool.com" but I would have to troll through about 12 months of tutorials to see something on the screen.
I'd work in a factory.
Also, this toy/experiment reminds me so much of Machinarium, I'm going to play it again right now.
Please also check http://fl.corge.net/ because it contains outrageous amounts of outstanding code.