I see people use this all the time as their main speaker? I usually ask why and if they say because it is a standard I stop talking music production. If they say they use them because they use it to hear the sound distorted then I am 100% in the conversation. These are used to hear what the "real world" crappy speaker system would sound like. Problem is EVERY speaker made the last 20 years is better than these speakers. The main response to why they use a NS-10 is "If it sounds good on NS10s then it'll sound good on anything."
I HATE HATE HATE the NS10 speaker. It was used because it was such a BAD speaker. In front of me I have Genelec speakers. They sound so good and clear. NS 10 sound like a brown paper bag with foam is covering the speaker and all low end and high end sounds were scooped out and I have my hands covering my ears!